HitPredict

Interactor 1: CDK2 (P23573)
Cyclin-dependent kinase 2 (EC 2.7.11.22) (EC 2.7.11.23) (Cell division control protein 2 cognate)
Gene: CDK2

Interactor 2: CCNE (P54733)
G1/S-specific cyclin-E (DmCycE)
Gene: CycE

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.932

The method score is based on:

Property Details
Experiments 8156587, 8980229, 22036573, 19966222, 11027291, unassigned4
Identification Methods affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation, experimental interaction detection
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0046427 - positive regulation of receptor signaling pathway via JAK-STAT
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 314
Dm

1 709
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Last updated: 15 Jul 2024