HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: 1433F (Q04917)
14-3-3 protein eta (Protein AS1)
Gene: YWHAH

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 2843 Hs			1 246
+	Hs
		626091 APC_HUMAN (1-2843): 0: 1316: 100.00		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		626089 APC_HUMAN (1-2843): 0: 1316: 100.00		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		626093 APC_HUMAN (1-2843): 0: 1316: 100.00		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		626055 APC_HUMAN (1-2843): 0: 1316: 100.00		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		626052 APC_HUMAN (1-2843): 0: 1316: 100.00		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		626056 APC_HUMAN (1-2843): 0: 1316: 100.00		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		257595 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		257593 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		257604 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		909649 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433E_HUMAN (1-244): 1.37e-141: 398: 62.71
+	Hs
		904674 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433G_HUMAN (1-246): 9.38e-138: 388: 86.99
+	Hs
		982101 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433F_HUMAN (1-246): 6.09e-136: 383: 100.00
+	Hs
		257597 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		257572 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		257566 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		257573 ANR17_HUMAN (1869-2843): 8.13e-62: 238: 14.08		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20
+	Hs
		927133 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433Z_HUMAN (3-245): 1.27e-107: 312: 74.49
+	Hs
		683415 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433B_HUMAN (3-245): 2.7e-107: 311: 75.51
+	Hs
		646967 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433T_HUMAN (3-245): 7.19e-106: 307: 71.43
+	Hs
		684093 ZEP3_HUMAN (802-2843): 1.1e-49: 198: 8.77		1433S_HUMAN (3-245): 2.76e-96: 283: 64.20