HitPredict

Interactor 1: APC (P25054)
Adenomatous polyposis coli protein (Protein APC) (Deleted in polyposis 2.5)
Gene: APC

Interactor 2: SYNE3 (Q6ZMZ3)
Nesprin-3 (KASH domain-containing protein 3) (KASH3) (Nuclear envelope spectrin repeat protein 3)
Gene: SYNE3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 2843 Hs			1 975
+	Hs
		626062 APC_HUMAN (1-2843): 0: 1316: 100.00		MYH10_HUMAN (1-826): 4.57e-32: 138: 11.81
+	Hs
		626291 APC_HUMAN (1-2843): 0: 1316: 100.00		MACF1_HUMAN (3-477): 8.96e-13: 75: 12.55
+	Hs
		164568 APC_HUMAN (1-2843): 0: 1316: 100.00		SPTN2_HUMAN (5-282): 3.82e-12: 73.1: 13.31
+	Hs
		626103 APC_HUMAN (1-2843): 0: 1316: 100.00		DYST_HUMAN (1-921): 4.17e-12: 72.9: 9.83
+	Hs
		626202 APC_HUMAN (1-2843): 0: 1316: 100.00		SYNE1_HUMAN (7-941): 2.97e-10: 66.8: 11.22
+	Hs
		1168763 NCOR2_HUMAN (821-2831): 1.68e-41: 171: 8.41		SYNE3_HUMAN (1-975): 1.69e-66: 243: 100.00
+	Hs
		724893 MICA3_HUMAN (1200-1800): 2.91e-09: 65.2: 13.62		MYH9_HUMAN (2-697): 2.15e-22: 106: 9.04
+	Mm
		561172 ANK2_MOUSE (1056-2841): 1.1e-15: 86.5: 9.74		SPTN1_MOUSE (5-666): 3.45e-13: 76.4: 9.94
+	Hs
		1045443 MICA3_HUMAN (1200-1800): 2.91e-09: 65.2: 13.62		SPTN1_HUMAN (5-666): 4.38e-13: 76: 9.94