HitPredict

Interactor 1: SIS1 (P25294)
Protein SIS1
Gene: SIS1

Interactor 2: YTM1 (Q12024)
Ribosome biogenesis protein YTM1 (Microtubule-associated protein YTM1)
Gene: YTM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.54	0.60	0.571

Property	Details
Experiments	37845327, 19536198
Identification Methods	proximity labelling technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 352 Sc			1 460
+	Hs
		681549 DNJA1_HUMAN (1-352): 2.53e-121: 357: 28.93		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		243532 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		FBXW7_HUMAN (190-457): 6.72e-60: 209: 18.38
+	Hs
		245646 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		TBL1X_HUMAN (47-276): 3.39e-44: 164: 14.23
+	Hs
		1309166 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		TBL1Y_HUMAN (47-274): 2.57e-43: 161: 13.93
+	Hs
		245562 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		TBL1X_HUMAN (47-276): 3.39e-44: 164: 14.23
+	Hs
		636407 DNJB1_HUMAN (5-352): 5.62e-109: 323: 34.09		TBL1Y_HUMAN (47-274): 2.57e-43: 161: 13.93
+	Hs
		243501 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		POC1A_HUMAN (8-234): 1.18e-31: 127: 13.48
+	Sc
		633227 MAS5_YEAST (1-352): 1.41e-111: 332: 28.13		MET30_YEAST (137-452): 3.86e-34: 137: 19.26
+	Sc
		628056 SIS1_YEAST (1-352): 6.96e-105: 313: 100.00		MET30_YEAST (137-452): 3.86e-34: 137: 19.26
+	Hs
		243354 DNJA2_HUMAN (2-352): 5.07e-121: 356: 28.09		WDR5_HUMAN (362-458): 1.09e-16: 82.9: 24.49
+	Hs
		279358 DNJB5_HUMAN (5-352): 6.21e-116: 341: 33.52		FBW1B_HUMAN (116-451): 1.16e-10: 65.5: 26.61
+	Hs
		1354513 DNJB4_HUMAN (5-352): 1.08e-112: 332: 34.08		FBW1B_HUMAN (116-451): 1.16e-10: 65.5: 26.61