Interactor 1: A5D6Q2 (A5D6Q2)
Nuclear receptor coactivator 3 (EC 2.3.1.48)
Gene: Ncoa3

Interactor 2: EP300 (B2RWS6)
Histone acetyltransferase p300 (p300 HAT) (EC 2.3.1.48) (E1A-associated protein p300) (Histone butyryltransferase p300) (EC 2.3.1.-) (Histone crotonyltransferase p300) (EC 2.3.1.-) (Protein 2-hydroxyisobutyryltransferase p300) (EC 2.3.1.-) (Protein lactyltransferas p300) (EC 2.3.1.-) (Protein propionyltransferase p300) (EC 2.3.1.-)
Gene: EP300

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 37415159
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Creb_binding~Nuc_rec_co-act
Common GO terms GO:0003682 - chromatin binding
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1353
Mm

1 2412
+ Hs
+ Mm
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 11Aug2025