HitPredict

Interactor 1: MAK11 (P20484)
Protein MAK11 (Maintenance of killer protein 11)
Gene: MAK11

Interactor 2: BRX1 (Q08235)
Ribosome biogenesis protein BRX1
Gene: BRX1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	17308036, 37968396
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000027 - ribosomal large subunit assembly GO:0005730 - nucleolus
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 414 Sc			1 291
+	Sc
		633152 MAK11_YEAST (1-414): 1.24e-96: 296: 100.00		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		633159 MAK11_YEAST (1-414): 1.24e-96: 296: 100.00		RPF1_YEAST (4-252): 5.86e-52: 173: 14.40
+	Sc
		633157 MAK11_YEAST (1-414): 1.24e-96: 296: 100.00		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		633205 MAK11_YEAST (1-414): 1.24e-96: 296: 100.00		SSF2_YEAST (10-197): 8.36e-33: 127: 15.17
+	Hs
		1446767 PK1IP_HUMAN (10-412): 5.05e-71: 230: 23.23		SSF1_HUMAN (12-281): 5.7e-45: 160: 12.87
+	Hs
		1351486 NLE1_HUMAN (268-412): 1.4e-16: 83.4: 15.13		BRX1_HUMAN (26-286): 1.93e-85: 261: 47.91
+	Hs
		1435608 NLE1_HUMAN (268-412): 1.4e-16: 83.4: 15.13		RPF2_HUMAN (1-285): 3.54e-77: 238: 17.57
+	Sc
		673557 NLE1_YEAST (269-414): 1.72e-14: 77.2: 11.49		RPF2_YEAST (6-282): 1.45e-61: 199: 16.84
+	Sc
		673560 NLE1_YEAST (269-414): 1.72e-14: 77.2: 11.49		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64
+	Sc
		804638 COPA_YEAST (24-182): 5.95e-13: 73: 16.56		SSF1_YEAST (10-197): 9.09e-34: 129: 15.64