HitPredict

Interactor 1: PWP2 (P25635)
Periodic tryptophan protein 2 (U three protein 1) (U3 small nucleolar RNA-associated protein 1) (U3 snoRNA-associated protein 1)
Gene: PWP2

Interactor 2: RL1D1 (P36144)
Ribosome biogenesis protein UTP30 (U3 snoRNP-associated protein UTP30)
Gene: UTP30

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.716

Property	Details
Experiments	11805826, 12150911, 16429126, 35650250, 37968396
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0030686 - 90S preribosome GO:0032040 - small-subunit processome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 923 Sc			1 274
+	Sc
		635573 PWP2_YEAST (1-923): 0: 650: 100.00		CIC1_YEAST (68-260): 4.34e-41: 147: 20.81
+	Sc
		733617 UTP12_YEAST (1-122): 1.57e-21: 103: 15.20		RL1D1_YEAST (1-274): 8.37e-106: 309: 100.00
+	Hs
		152848 APAF_HUMAN (451-834): 2.56e-50: 195: 12.87		RL1D1_HUMAN (8-256): 4.72e-57: 191: 24.90
+	Hs
		281204 WDR5_HUMAN (546-909): 5.2e-38: 147: 7.95		RL1D1_HUMAN (8-256): 4.72e-57: 191: 24.90
+	Hs
		281365 SNR40_HUMAN (143-502): 1.03e-16: 84.7: 22.28		RL1D1_HUMAN (8-256): 4.72e-57: 191: 24.90
+	Hs
		281444 NLE1_HUMAN (669-882): 5.38e-12: 71: 11.66		RL1D1_HUMAN (8-256): 4.72e-57: 191: 24.90
+	Sc
		754225 UTP12_YEAST (1-122): 1.57e-21: 103: 15.20		CIC1_YEAST (68-260): 4.34e-41: 147: 20.81