HitPredict

Interactor 1: TAH1 (P25638)
TPR repeat-containing protein associated with Hsp90
Gene: TAH1

Interactor 2: RUVB1 (Q03940)
RuvB-like protein 1 (RUVBL1) (EC 3.6.4.12) (TIP49-homology protein 1) (TIP49a homolog)
Gene: RVB1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.91	0.60	0.742

Property	Details
Experiments	26831523, 15766533, 16554755, 28648606, 33826901, 37968396, 18268103
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000492 - box C/D snoRNP assembly GO:0005634 - nucleus GO:0050821 - protein stabilization GO:0097255 - R2TP complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 111 Sc			1 463
+	Mm
		888062 PPP5_MOUSE (1-107): 3.3e-33: 121: 20.37		RUVB1_MOUSE (2-461): 0: 682: 67.83
+	Mm
		888118 RPAP3_MOUSE (2-108): 4.66e-27: 105: 23.15		RUVB1_MOUSE (2-461): 0: 682: 67.83
+	Hs
		1332520 RPAP3_HUMAN (2-107): 8.47e-27: 104: 24.30		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Mm
		1141243 PPP5_MOUSE (1-107): 3.3e-33: 121: 20.37		RUVB2_MOUSE (1-458): 0: 636: 41.09
+	Hs
		1332519 RPAP3_HUMAN (2-107): 8.47e-27: 104: 24.30		RUVB2_HUMAN (1-458): 0: 637: 41.09
+	Hs
		685119 STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16		RUVB1_HUMAN (2-461): 0: 682: 67.61
+	Sc
		635717 TAH1_YEAST (1-111): 5.74e-33: 112: 100.00		RUVB2_YEAST (15-463): 0: 622: 41.15
+	Hs
		685116 STIP1_HUMAN (4-110): 5.68e-09: 54: 17.16		RUVB2_HUMAN (1-458): 0: 637: 41.09