HitPredict

Interactor 1: LCK (P06239)
Tyrosine-protein kinase Lck (EC 2.7.10.2) (Leukocyte C-terminal Src kinase) (LSK) (Lymphocyte cell-specific protein-tyrosine kinase) (Protein YT16) (Proto-oncogene Lck) (T cell-specific protein-tyrosine kinase) (p56-LCK)
Gene: LCK

Interactor 2: PHAR4 (Q8IZ21)
Phosphatase and actin regulator 4
Gene: PHACTR4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 509 Hs			1 702
+	Hs
		433883 LYN_HUMAN (1-509): 0: 582: 62.72		PHAR4_HUMAN (1-702): 3.04e-73: 252: 100.00
+	Hs
		411889 LCK_HUMAN (1-509): 0: 661: 100.00		MACF1_HUMAN (497-699): 3.78e-37: 152: 17.96
+	Hs
		411682 LCK_HUMAN (1-509): 0: 661: 100.00		DYST_HUMAN (477-699): 6.74e-36: 148: 17.83
+	Hs
		411582 LCK_HUMAN (1-509): 0: 661: 100.00		MUC1_HUMAN (4-494): 4.09e-26: 117: 9.20
+	Hs
		337500 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		PHAR4_HUMAN (1-702): 3.04e-73: 252: 100.00
+	Hs
		257128 SRC_HUMAN (20-507): 0: 586: 55.00		PHAR2_HUMAN (9-702): 2.51e-39: 156: 35.81
+	Hs
		434078 LYN_HUMAN (1-509): 0: 582: 62.72		MACF1_HUMAN (497-699): 3.78e-37: 152: 17.96
+	Hs
		433710 LYN_HUMAN (1-509): 0: 582: 62.72		DYST_HUMAN (477-699): 6.74e-36: 148: 17.83
+	Hs
		203198 LCK_HUMAN (1-509): 0: 661: 100.00		SYNJ1_HUMAN (12-354): 5.61e-10: 65: 10.98
+	Hs
		166024 FYN_HUMAN (30-507): 0: 586: 59.01		SYNJ2_HUMAN (57-579): 1.23e-26: 118: 12.09
+	Hs
		522749 SRC_HUMAN (20-507): 0: 586: 55.00		MUC1_HUMAN (4-494): 4.09e-26: 117: 9.20
+	Hs
		433560 LYN_HUMAN (1-509): 0: 582: 62.72		MUC1_HUMAN (4-494): 4.09e-26: 117: 9.20
+	Hs
		297808 LYN_HUMAN (1-509): 0: 582: 62.72		K0754_HUMAN (100-652): 9.48e-20: 97: 10.70
+	Hs
		166023 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		SYNJ2_HUMAN (57-579): 1.23e-26: 118: 12.09
+	Hs
		337335 ABL1_HUMAN (49-502): 8.1e-171: 513: 42.21		MUC1_HUMAN (4-494): 4.09e-26: 117: 9.20