Interactor 1: MSH2 (P25847)
DNA mismatch repair protein MSH2 (MutS protein homolog 2)
Gene: MSH2

Interactor 2: MSH6 (Q03834)
DNA mismatch repair protein MSH6 (MutS protein homolog 6) (Postmeiotic segregation protein 3)
Gene: MSH6

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.993

The method score is based on:

Property Details
Experiments 9545323, 8600025, 8816473, 11805826, 11805837, 12529393, 11237611, 10970737, 11005803, 9374523, 12509278, 16214425, 12820877, 10480869, 9819445, 16303135, 26680658, 17720936, 31480444, 17996701 and 13 others

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Identification Methods biochemical, coimmunoprecipitation, tandem affinity purification, anti tag coimmunoprecipitation, pull down, two hybrid, enzymatic study, fluorescent resonance energy transfer, affinity chromatography technology, anti bait coimmunoprecipitation and 2 others

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Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains MutS_I~MutS_I, MutS_I~MutS_II, MutS_I~MutS_III, MutS_I~MutS_V, MutS_II~MutS_III, MutS_II~MutS_V, MutS_III~MutS_III, MutS_III~MutS_V, MutS_V~MutS_V
Common GO terms GO:0000400 - four-way junction DNA binding
GO:0000710 - meiotic mismatch repair
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0006298 - mismatch repair
and 6 others

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Homologous interactions 13

Homologous interactions

Color coding for hit scores

1 964
Sc

1 1242
+ Mm
+ Hs
+ Dr
+ Hs
+ At
+ Hs
+ At
+ Sc
+ At
+ Ce
+ Ec
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024