HitPredict

Interactor 1: EPHA1 (P21709)
Ephrin type-A receptor 1 (hEpha1) (EC 2.7.10.1) (EPH tyrosine kinase) (EPH tyrosine kinase 1) (Erythropoietin-producing hepatoma receptor) (Tyrosine-protein kinase receptor EPH)
Gene: EPHA1

Interactor 2: BI2L1 (Q9UHR4)
BAR/IMD domain-containing adapter protein 2-like 1 (Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1) (BAI1-associated protein 2-like protein 1) (Insulin receptor tyrosine kinase substrate)
Gene: BAIAP2L1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PK_Tyr_Ser-Thr~SH3_9
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 976 Hs			1 511
+	Hs
		1147458 EPHA7_HUMAN (2-975): 0: 1125: 43.22		BI2L1_HUMAN (1-511): 8.26e-169: 488: 100.00
+	Hs
		932150 EPHA4_HUMAN (5-975): 0: 1110: 43.50		BI2L1_HUMAN (1-511): 8.26e-169: 488: 100.00
+	Hs
		710913 EPHB2_HUMAN (27-975): 0: 1109: 40.81		BI2L1_HUMAN (1-511): 8.26e-169: 488: 100.00
+	Hs
		710552 EPHA2_HUMAN (24-976): 0: 1053: 49.90		BI2L1_HUMAN (1-511): 8.26e-169: 488: 100.00
+	Hs
		1147466 EPHA7_HUMAN (2-975): 0: 1125: 43.22		BAIP2_HUMAN (6-505): 1.43e-118: 361: 39.55
+	Hs
		932156 EPHA4_HUMAN (5-975): 0: 1110: 43.50		BAIP2_HUMAN (6-505): 1.43e-118: 361: 39.55
+	Hs
		710918 EPHB2_HUMAN (27-975): 0: 1109: 40.81		BAIP2_HUMAN (6-505): 1.43e-118: 361: 39.55
+	Hs
		1147464 EPHA7_HUMAN (2-975): 0: 1125: 43.22		PACN2_HUMAN (8-401): 3.85e-86: 275: 13.07
+	Hs
		932155 EPHA4_HUMAN (5-975): 0: 1110: 43.50		PACN2_HUMAN (8-401): 3.85e-86: 275: 13.07
+	Hs
		710917 EPHB2_HUMAN (27-975): 0: 1109: 40.81		PACN2_HUMAN (8-401): 3.85e-86: 275: 13.07
+	Hs
		931915 EPHA5_HUMAN (3-975): 0: 1109: 41.71		PACN2_HUMAN (8-401): 3.85e-86: 275: 13.07
+	Hs
		1147356 EPHA7_HUMAN (2-975): 0: 1125: 43.22		MTSS2_HUMAN (18-334): 2.75e-53: 194: 14.37
+	Hs
		710558 EPHA2_HUMAN (24-976): 0: 1053: 49.90		PACN3_HUMAN (7-400): 5.46e-74: 242: 12.71
+	Hs
		710326 EPHA2_HUMAN (24-976): 0: 1053: 49.90		MTSS2_HUMAN (18-334): 2.75e-53: 194: 14.37
+	Hs
		710840 EPHB2_HUMAN (27-975): 0: 1109: 40.81		ITSN1_HUMAN (6-491): 1.89e-27: 119: 11.80
+	Hs
		710527 EPHA2_HUMAN (24-976): 0: 1053: 49.90		ITSN2_HUMAN (225-399): 4.89e-10: 64.6: 14.29
+	Rn
		580490 INSR_RAT (391-882): 7.94e-131: 430: 26.99		BI2L1_RAT (1-511): 1.52e-157: 459: 86.82
+	Hs
		720364 UFO_HUMAN (274-914): 3.8e-156: 485: 25.11		BAIP2_HUMAN (6-505): 1.43e-118: 361: 39.55