HitPredict

Interactor 1: S10A8 (P27005)
Protein S100-A8 (Calgranulin-A) (Chemotactic cytokine CP-10) (Leukocyte L1 complex light chain) (Migration inhibitory factor-related protein 8) (MRP-8) (p8) (Pro-inflammatory S100 cytokine) (S100 calcium-binding protein A8)
Gene: S100a8

Interactor 2: S10A9 (P31725)
Protein S100-A9 (Calgranulin-B) (Leukocyte L1 complex heavy chain) (Migration inhibitory factor-related protein 14) (MRP-14) (p14) (S100 calcium-binding protein A9)
Gene: S100a9

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 1.00 0.743

The method score is based on:

Property Details
Experiments 21228116, 9867828
Identification Methods anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains S_100~S_100
Common GO terms GO:0002523 - leukocyte migration involved in inflammatory response
GO:0002790 - peptide secretion
GO:0002793 - positive regulation of peptide secretion
GO:0005509 - calcium ion binding
GO:0005615 - extracellular space
and 15 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 89
Mm

1 113
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024