HitPredict

Interactor 1: AVR2A (P27037)
Activin receptor type-2A (EC 2.7.11.30) (Activin receptor type IIA) (ACTR-IIA) (ACTRIIA)
Gene: ACVR2A

Interactor 2: PE2R3 (P43115)
Prostaglandin E2 receptor EP3 subtype (PGE receptor EP3 subtype) (PGE2 receptor EP3 subtype) (PGE2-R) (Prostanoid EP3 receptor)
Gene: PTGER3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	7tm_1~Pkinase
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 513 Hs			1 390
+	Hs
		793098 AVR2B_HUMAN (4-513): 2.64e-141: 418: 67.12		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		738310 BMR1A_HUMAN (59-488): 2.92e-128: 385: 33.41		PE2R3_HUMAN (1-390): 1.16e-69: 226: 100.00
+	Hs
		600869 BMR1A_HUMAN (59-488): 2.92e-128: 385: 33.41		TA2R_HUMAN (43-380): 6.15e-65: 212: 33.73
+	Hs
		723275 BMR1A_HUMAN (59-488): 2.92e-128: 385: 33.41		APJ_HUMAN (37-390): 1.01e-63: 210: 14.41