HitPredict

Interactor 1: NOS2 (P35228)
Nitric oxide synthase, inducible (EC 1.14.13.39) (Hepatocyte NOS) (HEP-NOS) (Inducible NO synthase) (Inducible NOS) (iNOS) (NOS type II) (Peptidyl-cysteine S-nitrosylase NOS2)
Gene: NOS2

Interactor 2: SPSB1 (Q96BD6)
SPRY domain-containing SOCS box protein 1 (SSB-1)
Gene: SPSB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.77	0.60	0.680

Property	Details
Experiments	21199876, 21549100, 20603330, 23438482
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1153 Hs			1 273
+	Hs
		718522 NOS2_HUMAN (1-1153): 0: 1800: 100.00		SPSB4_HUMAN (1-273): 1.02e-119: 345: 74.73
+	Hs
		718529 NOS2_HUMAN (1-1153): 0: 1800: 100.00		SPSB2_HUMAN (1-273): 3.23e-94: 280: 50.18
+	Hs
		472681 NOS2_HUMAN (1-1153): 0: 1800: 100.00		FBSP1_HUMAN (22-230): 1.1e-69: 218: 36.02
+	Hs
		718513 NOS2_HUMAN (1-1153): 0: 1800: 100.00		HERC1_HUMAN (22-225): 8.34e-39: 146: 20.38
+	Hs
		718518 NOS2_HUMAN (1-1153): 0: 1800: 100.00		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		560208 NCPR_HUMAN (502-1128): 0: 749: 29.78		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11
+	Hs
		1172144 NDOR1_HUMAN (536-1129): 0: 580: 26.71		TRI67_HUMAN (52-232): 7.58e-36: 137: 17.11