HitPredict

Interactor 1: DPP4 (P27487)
Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]
Gene: DPP4

Interactor 2: DPP4 (P27487)
Dipeptidyl peptidase 4 (EC 3.4.14.5) (ADABP) (Adenosine deaminase complexing protein 2) (ADCP-2) (Dipeptidyl peptidase IV) (DPP IV) (T-cell activation antigen CD26) (TP103) (CD antigen CD26) [Cleaved into: Dipeptidyl peptidase 4 membrane form (Dipeptidyl peptidase IV membrane form); Dipeptidyl peptidase 4 soluble form (Dipeptidyl peptidase IV soluble form)]
Gene: DPP4

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.68 1.00 0.828

The method score is based on:

Property Details
Experiments 34709727, 22001206
Identification Methods affinity chromatography technology, proximity labelling technology, cosedimentation in solution, circular dichroism, comigration in gel electrophoresis
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains DPPIV_N~DPPIV_N, DPPIV_N~Peptidase_S9, Peptidase_S9~Peptidase_S9
Common GO terms GO:0001618 - virus receptor activity
GO:0001662 - behavioral fear response
GO:0001666 - response to hypoxia
GO:0002020 - protease binding
GO:0004177 - aminopeptidase activity
and 36 others

more...
Homologous interactions 10

Homologous interactions

Color coding for hit scores

1 766
Hs

1 766
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Last updated: 15 Jul 2024