Interactor 1: AMPL (P14904)
Vacuolar aminopeptidase 1 (EC 3.4.11.22) (Aminopeptidase yscI) (Leucine aminopeptidase IV) (LAPIV) (Lysosomal aminopeptidase III) (Polypeptidase) (Vacuolar aminopeptidase I)
Gene: APE1

Interactor 2: AMPL (P14904)
Vacuolar aminopeptidase 1 (EC 3.4.11.22) (Aminopeptidase yscI) (Leucine aminopeptidase IV) (LAPIV) (Lysosomal aminopeptidase III) (Polypeptidase) (Vacuolar aminopeptidase I)
Gene: APE1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 1.00 0.972

The method score is based on:

Property Details
Experiments 10688190, 26208681, 28027291, 27266708, 11283351, 27320913, 18719252, 19343713
Identification Methods two hybrid, x-ray crystallography, pull down, biochemical, blue native page
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Peptidase_M18~Peptidase_M18
Common GO terms GO:0000324 - fungal-type vacuole
GO:0005737 - cytoplasm
GO:0006508 - proteolysis
GO:0008270 - zinc ion binding
GO:0032258 - cytoplasm to vacuole targeting by the Cvt pathway
and 2 others

more...

Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 514
Sc

1 514
+ Sc
+ Hs
+ Sc
+ Ce

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024