HitPredict

Interactor 1: CBL (P22682)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Interactor 2: SLAP1 (Q60898)
Src-like-adapter (Src-like-adapter protein 1) (SLAP-1) (mSLAP)
Gene: Sla

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	12024036
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Mm			1 281
+	Mm
		571266 CBL_MOUSE (1-913): 0: 900: 100.00		FGR_MOUSE (5-280): 1.63e-99: 302: 24.34
+	Mm
		431323 CBL_MOUSE (1-913): 0: 900: 100.00		SRC_MOUSE (2-280): 4.51e-99: 301: 25.90
+	Mm
		651485 CBL_MOUSE (1-913): 0: 900: 100.00		FYN_MOUSE (9-280): 7.27e-99: 301: 26.25
+	Mm
		651476 CBL_MOUSE (1-913): 0: 900: 100.00		LYN_MOUSE (5-280): 2.14e-96: 294: 25.50
+	Mm
		465767 CBL_MOUSE (1-913): 0: 900: 100.00		HCK_MOUSE (2-280): 6.13e-96: 293: 26.80
+	Mm
		440271 CBL_MOUSE (1-913): 0: 900: 100.00		LCK_MOUSE (2-280): 8.45e-96: 292: 26.65
+	Hs
		462986 CBL_HUMAN (1-913): 0: 870: 90.83		YES_HUMAN (17-280): 1.12e-99: 303: 26.55
+	Hs
		486660 CBL_HUMAN (1-913): 0: 870: 90.83		FGR_HUMAN (2-280): 1.94e-99: 302: 24.76
+	Hs
		440368 CBL_HUMAN (1-913): 0: 870: 90.83		FYN_HUMAN (9-280): 2.57e-98: 300: 25.91
+	Hs
		473369 CBL_HUMAN (1-913): 0: 870: 90.83		HCK_HUMAN (2-280): 1.86e-97: 297: 27.04
+	Hs
		463333 CBL_HUMAN (1-913): 0: 870: 90.83		LYN_HUMAN (5-280): 1.31e-96: 295: 25.83
+	Hs
		439949 CBL_HUMAN (1-913): 0: 870: 90.83		LCK_HUMAN (2-280): 2.63e-95: 291: 25.99
+	Mm
		362435 CBL_MOUSE (1-913): 0: 900: 100.00		ABL1_MOUSE (2-267): 4.11e-71: 238: 20.28
+	Mm
		651517 CBL_MOUSE (1-913): 0: 900: 100.00		ITK_MOUSE (3-279): 1.49e-73: 238: 18.33
+	Mm
		651486 CBL_MOUSE (1-913): 0: 900: 100.00		CSK_MOUSE (20-274): 6.58e-72: 229: 19.01
+	Mm
		651560 CBL_MOUSE (1-913): 0: 900: 100.00		SLAP2_MOUSE (10-247): 1.83e-68: 214: 43.85
+	Hs
		362162 CBL_HUMAN (1-913): 0: 870: 90.83		ABL1_HUMAN (2-267): 2.82e-71: 239: 20.28
+	Mm
		651529 CBL_MOUSE (1-913): 0: 900: 100.00		GRB2_MOUSE (28-164): 4.45e-57: 184: 30.00
+	Hs
		72378 CBL_HUMAN (1-913): 0: 870: 90.83		A9UF07_HUMAN (13-248): 3.74e-56: 196: 24.62
+	Mm
		313429 CBL_MOUSE (1-913): 0: 900: 100.00		GRAP2_MOUSE (43-160): 2.28e-11: 65.1: 36.13