HitPredict

Interactor 1: ERD21 (P24390)
ER lumen protein-retaining receptor 1 (KDEL endoplasmic reticulum protein retention receptor 1) (KDEL receptor 1) (Putative MAPK-activating protein PM23)
Gene: KDELR1

Interactor 2: P2RY2 (P41231)
P2Y purinoceptor 2 (P2Y2) (ATP receptor) (P2U purinoceptor 1) (P2U1) (P2U receptor 1) (Purinergic receptor)
Gene: P2RY2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 212 Hs			1 377
+	Hs
		664959 ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00		CCR9_HUMAN (1-315): 1.27e-86: 268: 24.46
+	Hs
		225364 ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99		LPAR6_HUMAN (25-310): 1.54e-85: 264: 33.45
+	Hs
		225367 ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99		CXCR4_HUMAN (7-329): 3.6e-75: 238: 24.47
+	Hs
		225369 ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99		GPR17_HUMAN (15-346): 3.12e-74: 236: 30.15
+	Hs
		664948 ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00		APJ_HUMAN (2-345): 4.07e-73: 234: 22.73
+	Hs
		664963 ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00		PAR2_HUMAN (34-320): 2.57e-36: 137: 31.16
+	Hs
		225373 ERD23_HUMAN (1-211): 1.51e-83: 248: 72.99		P2RY8_HUMAN (34-370): 5.37e-35: 133: 30.81
+	Hs
		664986 ERD21_HUMAN (1-212): 1.2e-82: 246: 100.00		P2RY8_HUMAN (34-370): 5.37e-35: 133: 30.81