Interactor 1: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Interactor 2: DAXX (Q9UER7)
Death domain-associated protein 6 (Daxx) (hDaxx) (ETS1-associated protein 1) (EAP1) (Fas death domain-associated protein)
Gene: DAXX

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.60 0.762

The method score is based on:

Property Details
Experiments 17081986, 32545337, 12150977, 21474068, 10525530, 15710327, 10669754, 11244500, 10684855, 34795231, 20972456, 17360386, 21482821, 23222847, 12529400, 21840486
Identification Methods affinity chromatography technology, pull down, two hybrid, proximity labelling technology, enzymatic study, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005730 - nucleolus
GO:0005829 - cytosol
and 7 others

more...

Homologous interactions 5

Homologous interactions

Color coding for hit scores

1 882
Hs

1 740
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024