Protein: C5AR2
C5a anaphylatoxin chemotactic receptor 2 (Complement component 5a receptor 2) (G-protein coupled receptor 77)

Gene: C5AR2
Organism: Homo sapiens
Interactions: 75
UniProt ID: Q9P296

Gene Ontology (top 5):
GO:0002430 - complement receptor mediated signaling pathway
GO:0004878 - complement component C5a receptor activity
GO:0004930 - G protein-coupled receptor activity
GO:0005886 - plasma membrane
GO:0006935 - chemotaxis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

171775

GAK
Cyclin-G-associated kinase

2

1

High-throughput

0.726

High

755641

TTK
Dual specificity protein kinase TTK

2

10

High-throughput

0.726

High

1060031

SCN1B
Sodium channel regulatory subunit beta-1

1

0

High-throughput

0.663

High

297283

PRAF3
PRA1 family protein 3

2

6

High-throughput

0.628

High

607666

PTN2
Tyrosine-protein phosphatase non-receptor type 2

2

20

High-throughput

0.628

High

912722

CTR2
Cationic amino acid transporter 2

2

18

High-throughput

0.628

High

931306

AT12A
Potassium-transporting ATPase alpha chain 2

2

20

High-throughput

0.628

High

943147

STX17
Syntaxin-17

2

1

High-throughput

0.628

High

1103804

PLD1
Phospholipase D1

2

4

High-throughput

0.628

High

1217400

AB17B
Alpha/beta hydrolase domain-containing protein 17B

2

14

High-throughput

0.628

High

1228857

LMBD2
G-protein coupled receptor-associated protein LMBRD2

2

11

High-throughput

0.628

High

1369316

EDA
Ectodysplasin-A

2

4

High-throughput

0.628

High

1387075

COQ8B
Atypical kinase COQ8B, mitochondrial

2

11

High-throughput

0.628

High

1392379

AB17A
Alpha/beta hydrolase domain-containing protein 17A

2

13

High-throughput

0.628

High

1401249

PANX1
Pannexin-1

2

3

High-throughput

0.628

High

1414837

ABHD6
Monoacylglycerol lipase ABHD6

2

2

High-throughput

0.628

High

1417162

S12A9
Solute carrier family 12 member 9

2

20

High-throughput

0.628

High

1433364

GOLP3
Golgi phosphoprotein 3

2

6

High-throughput

0.628

High

1454435

S12A7
Solute carrier family 12 member 7

2

20

High-throughput

0.628

High

122655

UBXN8
UBX domain-containing protein 8

2

1

High-throughput

0.574

High

173759

BTAF1
TATA-binding protein-associated factor 172

2

13

High-throughput

0.574

High

220031

XRCC3
DNA repair protein XRCC3

2

3

High-throughput

0.574

High

249269

MA1A2
Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB

2

1

High-throughput

0.574

High

297075

DHRS3
Short-chain dehydrogenase/reductase 3

2

3

High-throughput

0.574

High

483978

HMOX1
Heme oxygenase 1

2

6

High-throughput

0.574

High

522795

NR2F6
Nuclear receptor subfamily 2 group F member 6

2

9

High-throughput

0.574

High

611399

PTN1
Tyrosine-protein phosphatase non-receptor type 1

2

20

High-throughput

0.574

High

665150

COT2
COUP transcription factor 2

2

9

High-throughput

0.574

High

849045

PTN9
Tyrosine-protein phosphatase non-receptor type 9

2

19

High-throughput

0.574

High

1231480

ATLA3
Atlastin-3

2

17

High-throughput

0.574

High

1234005

ASPH2
Aspartate beta-hydroxylase domain-containing protein 2

2

1

High-throughput

0.574

High

1243253

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

8

High-throughput

0.574

High

1287611

ADCK1
AarF domain-containing protein kinase 1

2

11

High-throughput

0.574

High

1325701

GUF1
Translation factor GUF1, mitochondrial

2

5

High-throughput

0.574

High

1336979

SIMC1
SUMO-interacting motif-containing protein 1

2

2

High-throughput

0.574

High

1340117

ATLA2
Atlastin-2

2

17

High-throughput

0.574

High

1386106

EVI5L
EVI5-like protein

2

6

High-throughput

0.574

High

1388352

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

2

1

High-throughput

0.574

High

1412548

GCP2
Gamma-tubulin complex component 2

2

17

High-throughput

0.574

High

1433347

GLP3L
Golgi phosphoprotein 3-like

2

6

High-throughput

0.574

High

1435767

AT133
Polyamine-transporting ATPase 13A3

2

20

High-throughput

0.574

High

1449390

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

2

6

High-throughput

0.574

High

343089

HERC2
E3 ubiquitin-protein ligase HERC2

1

8

High-throughput

0.541

High

1040228

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

15

High-throughput

0.541

High

1122364

SCRIB
Protein scribble homolog

1

9

High-throughput

0.541

High

1292298

S2611
Sodium-independent sulfate anion transporter

1

1

High-throughput

0.541

High

1317124

ABCA7
Phospholipid-transporting ATPase ABCA7

1

2

High-throughput

0.541

High

256182

S19A2
Thiamine transporter 1

1

9

High-throughput

0.536

High

562818

CY24A
Cytochrome b-245 light chain

1

1

High-throughput

0.536

High

565725

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

20

High-throughput

0.536

High

1310847

LRC8A
Volume-regulated anion channel subunit LRRC8A

1

11

High-throughput

0.536

High

1347252

EXOC6
Exocyst complex component 6

1

5

High-throughput

0.536

High

1307709

PLDX1
Plexin domain-containing protein 1

1

0

High-throughput

0.518

High

1203144

SGMR2
Sigma intracellular receptor 2

1

0

High-throughput

0.513

High

226460

SNG2
Synaptogyrin-2

1

5

High-throughput

0.494

High

1136692

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

1

High-throughput

0.494

High

50719

HACL2
2-hydroxyacyl-CoA lyase 2

1

1

High-throughput

0.489

High

844044

HD
Huntingtin

1

5

High-throughput

0.489

High

997168

TBA4A
Tubulin alpha-4A chain

1

4

High-throughput

0.489

High

1102281

ATM
Serine-protein kinase ATM

1

20

High-throughput

0.489

High

1273074

DPH6
Diphthine--ammonia ligase

1

5

High-throughput

0.489

High

1363876

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

7

High-throughput

0.489

High

1371208

GLMN
Glomulin

1

4

High-throughput

0.489

High

1408244

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

14

High-throughput

0.489

High

1454434

TELO2
Telomere length regulation protein TEL2 homolog

1

2

High-throughput

0.489

High

1454433

DCDC2
Doublecortin domain-containing protein 2

1

1

High-throughput

0.470

High

839512

PI4KA
Phosphatidylinositol 4-kinase alpha

1

14

High-throughput

0.445

High

1195705

Q4LE69
Phosphatidylinositol 4-kinase alpha

1

12

High-throughput

0.437

High

1060302

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

0

High-throughput

0.328

High

1337371

GSTCD
Glutathione S-transferase C-terminal domain-containing protein

2

0

High-throughput

0.328

High

1359161

GLMP
Glycosylated lysosomal membrane protein

2

0

High-throughput

0.328

High

1244790

HAGHL
Hydroxyacylglutathione hydrolase-like protein

1

0

High-throughput

0.282

High

1358726

SRALN
Sarcoplasmic/endoplasmic reticulum calcium ATPase regulator ARLN

1

0

High-throughput

0.282

High

1361465

TM234
Transmembrane protein 234

1

0

High-throughput

0.282

High

1407352

ACON
Aconitate hydratase, mitochondrial

1

0

High-throughput

0.282

High


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Last updated: 11Aug2025