HitPredict

Interactor 1: P121C (A8CG34)
Nuclear envelope pore membrane protein POM 121C (Nuclear pore membrane protein 121-2) (POM121-2) (Pore membrane protein of 121 kDa C)
Gene: POM121C

Interactor 2: ESR2 (Q92731)
Estrogen receptor beta (ER-beta) (Nuclear receptor subfamily 3 group A member 2)
Gene: ESR2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	21182203
Identification Methods	cosedimentation through density gradient
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1229 Hs			1 530
+	Hs
		1367013 P121A_HUMAN (1-1229): 1.41e-75: 276: 93.45		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		590324 MUC1_HUMAN (292-1226): 2.09e-54: 210: 12.49		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		395433 MUC1_HUMAN (292-1226): 2.09e-54: 210: 12.49		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		1129670 MDC1_HUMAN (2-946): 7.87e-34: 144: 10.94		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		1367725 PCLO_HUMAN (277-1224): 3.75e-31: 136: 11.15		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		274214 ANR17_HUMAN (282-1164): 8.84e-23: 108: 14.54		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		76089 B4DET5_HUMAN (371-1229): 8.92e-62: 230: 99.65		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		1367250 TARA_HUMAN (11-1210): 8.29e-20: 98.8: 9.17		ESR2_HUMAN (1-530): 2.39e-157: 460: 100.00
+	Hs
		396114 MDC1_HUMAN (2-946): 7.87e-34: 144: 10.94		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		274071 ANR17_HUMAN (282-1164): 8.84e-23: 108: 14.54		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		396925 TARA_HUMAN (11-1210): 8.29e-20: 98.8: 9.17		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		396119 NCOA6_HUMAN (6-1226): 2.55e-16: 87.2: 8.52		ESR1_HUMAN (9-529): 3.59e-138: 413: 44.56
+	Hs
		274073 ANR17_HUMAN (282-1164): 8.84e-23: 108: 14.54		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		833976 SRCAP_HUMAN (3-971): 1.64e-22: 107: 11.28		HNF4A_HUMAN (94-502): 1.22e-107: 331: 23.30
+	Hs
		138959 BCL9_HUMAN (217-1227): 2.04e-16: 87.2: 9.36		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		404058 NCOA6_HUMAN (6-1226): 2.55e-16: 87.2: 8.52		GCR_HUMAN (3-495): 1.13e-103: 330: 22.64
+	Hs
		520042 MDC1_HUMAN (2-946): 7.87e-34: 144: 10.94		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520149 SRCAP_HUMAN (3-971): 1.64e-22: 107: 11.28		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		138962 BCL9_HUMAN (217-1227): 2.04e-16: 87.2: 9.36		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59
+	Hs
		520044 NCOA6_HUMAN (6-1226): 2.55e-16: 87.2: 8.52		ANDR_HUMAN (149-407): 8.13e-38: 150: 32.59