Interactor 1: AKT1 (P31749)
RAC-alpha serine/threonine-protein kinase (EC 2.7.11.1) (Protein kinase B) (PKB) (Protein kinase B alpha) (PKB alpha) (Proto-oncogene c-Akt) (RAC-PK-alpha)
Gene: AKT1
Interactor 2: DP13A (Q9UKG1)
DCC-interacting protein 13-alpha (Dip13-alpha) (Adapter protein containing PH domain, PTB domain and leucine zipper motif 1)
Gene: APPL1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.81 | 1.00 | 0.904 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25814554, 29523594, 12621049, 10490823, unassigned1126 |
| Identification Methods | two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, two hybrid array |
| Interaction Type | direct interaction, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | BAR_3~PH, PH~PH, PH~Pkinase |
| Common GO terms | GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0006606 - protein import into nucleus and 7 others more... |
| Homologous interactions | 6 |
Homologous interactions
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Last updated: 15 Jul 2024
