HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: UBP43 (Q70EL4)
Ubiquitin carboxyl-terminal hydrolase 43 (EC 3.4.19.12) (Deubiquitinating enzyme 43) (Ubiquitin thioesterase 43) (Ubiquitin-specific-processing protease 43)
Gene: USP43

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.50	0.652

Property	Details
Experiments	33961781, 36931259, 30135474, 19615732, 28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1123
+	Hs
		909724 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP43_HUMAN (1-1123): 0: 999: 100.00
+	Hs
		927206 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP43_HUMAN (1-1123): 0: 999: 100.00
+	Hs
		647034 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP43_HUMAN (1-1123): 0: 999: 100.00
+	Hs
		904762 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP43_HUMAN (1-1123): 0: 999: 100.00
+	Hs
		909722 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP31_HUMAN (99-993): 2.51e-160: 513: 41.05
+	Hs
		683479 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP31_HUMAN (99-993): 2.51e-160: 513: 41.05
+	Hs
		927203 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP31_HUMAN (99-993): 2.51e-160: 513: 41.05
+	Hs
		683310 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP4_HUMAN (3-713): 1.05e-157: 495: 25.03
+	Hs
		647032 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP31_HUMAN (99-993): 2.51e-160: 513: 41.05
+	Hs
		646740 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP11_HUMAN (84-724): 1.83e-153: 484: 24.37
+	Hs
		904758 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP31_HUMAN (99-993): 2.51e-160: 513: 41.05
+	Hs
		777027 1433E_HUMAN (3-243): 4.39e-144: 405: 65.43		UBP8_HUMAN (536-713): 5e-52: 201: 32.58
+	Hs
		683179 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP8_HUMAN (536-713): 5e-52: 201: 32.58
+	Mm
		910281 1433E_MOUSE (3-243): 4.39e-144: 405: 65.43		UBP8_MOUSE (536-713): 1.14e-51: 200: 33.15
+	Hs
		777029 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		UBP8_HUMAN (536-713): 5e-52: 201: 32.58
+	Hs
		647384 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP22_HUMAN (99-399): 2.86e-61: 220: 21.94
+	Hs
		646698 1433T_HUMAN (3-244): 3.24e-127: 361: 81.82		UBP8_HUMAN (536-713): 5e-52: 201: 32.58
+	Hs
		777025 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		UBP8_HUMAN (536-713): 5e-52: 201: 32.58
+	Hs
		110625 1433G_HUMAN (3-246): 1.91e-109: 317: 75.40		H3BND8_HUMAN (93-521): 1.73e-47: 186: 13.75
+	Hs
		683552 1433B_HUMAN (1-246): 3.48e-144: 404: 100.00		UBP32_HUMAN (292-537): 4.78e-13: 76.2: 5.69