HitPredict

Interactor 1: A0A087WW66 (A0A087WW66)
26S proteasome non-ATPase regulatory subunit 1
Gene: PSMD1

Interactor 2: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	35271311
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 914 Hs			1 241
+	Hs
		694 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94
+	Hs
		699 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91
+	Hs
		594615 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00
+	Hs
		688 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72
+	Hs
		689 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67
+	Hs
		832033 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94
+	Hs
		691 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27
+	Hs
		156342 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA7_HUMAN (17-241): 8.16e-79: 238: 13.54
+	Hs
		893734 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA6_HUMAN (17-240): 4.32e-77: 234: 14.91
+	Hs
		638180 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA4_HUMAN (8-240): 1.49e-75: 231: 17.72
+	Hs
		656297 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSA5_HUMAN (16-240): 7.6e-75: 228: 16.67
+	Hs
		656760 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB5_HUMAN (9-230): 4.76e-73: 224: 20.27
+	Hs
		690 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68
+	Hs
		656638 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB6_HUMAN (34-236): 8.15e-56: 180: 21.68
+	Hs
		695 A0A087WW66_HUMAN (1-914): 0: 1236: 100.00		PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62
+	Dm
		1278636 PSMD1_DROME (2-894): 0: 1056: 58.84		PSA5_DROME (16-240): 5.24e-75: 229: 17.37
+	Hs
		832152 PSMD1_HUMAN (1-914): 0: 1216: 95.91		PSB2_HUMAN (40-233): 2.78e-09: 57: 24.62
+	Dm
		1178951 PSMD1_DROME (2-894): 0: 1056: 58.84		Q7K148_DROME (19-230): 2.86e-69: 215: 18.43
+	Dm
		771411 PSMD1_DROME (2-894): 0: 1056: 58.84		PSB1_DROME (30-241): 2.46e-68: 212: 52.34
+	Dm
		47613 PSMD1_DROME (2-894): 0: 1056: 58.84		A0AQH0_DROME (34-235): 9.99e-64: 199: 26.24