HitPredict

Interactor 1: 1433T (P27348)
14-3-3 protein theta (14-3-3 protein T-cell) (14-3-3 protein tau) (Protein HS1)
Gene: YWHAQ

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.94	0.60	0.751

Property	Details
Experiments	21988832, 17353931, 33961781, 35271311, 36931259, 15324660, 15161933, 28514442, unassigned3799
Identification Methods	two hybrid, affinity chromatography technology, proximity labelling technology, pull down, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 245 Hs			1 1025
+	Hs
		971669 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MPRIP_HUMAN (1-1025): 9.69e-126: 410: 100.00
+	Mm
		972204 1433E_MOUSE (2-243): 1.32e-144: 406: 63.53		MPRIP_MOUSE (1-1024): 6.11e-117: 386: 88.01
+	Hs
		971813 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		691270 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		DLG5_HUMAN (647-1019): 8.92e-54: 207: 21.61
+	Hs
		691123 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MRCKG_HUMAN (599-998): 1.14e-44: 178: 19.48
+	Hs
		971646 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		691127 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		PKHA7_HUMAN (336-980): 2.5e-41: 167: 13.51
+	Hs
		972012 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		PKHA5_HUMAN (318-1019): 2.96e-36: 151: 13.24
+	Hs
		971623 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MRCKA_HUMAN (418-981): 1.19e-30: 133: 12.40
+	Hs
		691104 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MRCKA_HUMAN (418-981): 1.19e-30: 133: 12.40
+	Hs
		773148 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYH10_HUMAN (242-1024): 1.66e-21: 103: 8.45
+	Mm
		990028 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		MYH9_MOUSE (561-1013): 2.5e-17: 90.2: 12.80
+	Hs
		690784 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYH9_HUMAN (528-991): 3.25e-16: 86.3: 11.35
+	Mm
		989976 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		MYH10_MOUSE (540-1024): 6.42e-15: 82.1: 10.20
+	Hs
		691423 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		SLK_HUMAN (194-1010): 4.74e-15: 82.5: 9.73
+	Hs
		776794 1433E_HUMAN (2-243): 1.32e-144: 406: 63.53		MYH11_HUMAN (124-786): 5.18e-12: 72.4: 11.57
+	Hs
		690788 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYH11_HUMAN (124-786): 5.18e-12: 72.4: 11.57
+	Hs
		556897 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		MYH7_HUMAN (558-1009): 8.37e-12: 72.1: 10.92
+	Mm
		990062 1433Z_MOUSE (1-245): 3.08e-142: 399: 80.00		PLEC_MOUSE (494-979): 2.15e-11: 70.8: 14.60
+	Hs
		691026 1433T_HUMAN (1-245): 9.51e-142: 398: 100.00		PLEC_HUMAN (499-978): 3.11e-11: 70.1: 14.96