HitPredict

Interactor 1: CALX (P27824)
Calnexin (IP90) (Major histocompatibility complex class I antigen-binding protein p88) (p90)
Gene: CANX

Interactor 2: TYRO3 (Q06418)
Tyrosine-protein kinase receptor TYRO3 (EC 2.7.10.1) (Tyrosine-protein kinase BYK) (Tyrosine-protein kinase DTK) (Tyrosine-protein kinase RSE) (Tyrosine-protein kinase SKY) (Tyrosine-protein kinase TIF)
Gene: TYRO3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35384245
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005789 - endoplasmic reticulum membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 592 Hs			1 890
+	Hs
		698417 CALX_HUMAN (1-592): 0: 786: 100.00		UFO_HUMAN (14-874): 0: 621: 40.29
+	Hs
		170735 CLGN_HUMAN (11-546): 0: 652: 59.85		TYRO3_HUMAN (1-890): 0: 754: 100.00
+	Hs
		698405 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA3_HUMAN (125-814): 0: 559: 19.86
+	Hs
		698406 CALX_HUMAN (1-592): 0: 786: 100.00		EPHA8_HUMAN (116-808): 1.72e-170: 523: 20.08
+	Hs
		698744 CALX_HUMAN (1-592): 0: 786: 100.00		EPHAA_HUMAN (203-842): 1.82e-129: 415: 23.35
+	Hs
		697779 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		UFO_HUMAN (14-874): 0: 621: 40.29
+	Hs
		471993 CALX_HUMAN (1-592): 0: 786: 100.00		MET_HUMAN (495-790): 3.91e-65: 240: 41.67
+	Hs
		465416 CALX_HUMAN (1-592): 0: 786: 100.00		IGF1R_HUMAN (333-779): 3.4e-61: 228: 32.53
+	Hs
		439649 CALX_HUMAN (1-592): 0: 786: 100.00		INSR_HUMAN (292-790): 2.18e-60: 226: 31.15
+	Hs
		477210 CALX_HUMAN (1-592): 0: 786: 100.00		ROS1_HUMAN (279-787): 2.74e-55: 211: 30.76
+	Hs
		463904 CALX_HUMAN (1-592): 0: 786: 100.00		RET_HUMAN (514-790): 1.9e-55: 210: 39.93
+	Hs
		170630 CLGN_HUMAN (11-546): 0: 652: 59.85		MET_HUMAN (495-790): 3.91e-65: 240: 41.67
+	Hs
		170627 CLGN_HUMAN (11-546): 0: 652: 59.85		IGF1R_HUMAN (333-779): 3.4e-61: 228: 32.53
+	Hs
		170616 CLGN_HUMAN (11-546): 0: 652: 59.85		INSR_HUMAN (292-790): 2.18e-60: 226: 31.15
+	Hs
		541353 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR1_HUMAN (6-138): 6.61e-16: 84.4: 20.83
+	Hs
		641121 CALX_HUMAN (1-592): 0: 786: 100.00		FGFR2_HUMAN (5-139): 7.27e-15: 81: 20.55
+	Hs
		170626 CLGN_HUMAN (11-546): 0: 652: 59.85		RET_HUMAN (514-790): 1.9e-55: 210: 39.93
+	Hs
		170639 CLGN_HUMAN (11-546): 0: 652: 59.85		FGFR1_HUMAN (6-138): 6.61e-16: 84.4: 20.83
+	Hs
		471992 CALR_HUMAN (67-470): 1.2e-141: 418: 38.33		MET_HUMAN (495-790): 3.91e-65: 240: 41.67
+	Rn
		580424 CALR_RAT (67-470): 7.83e-147: 431: 37.35		INSR_RAT (292-790): 2.46e-59: 223: 31.17