HitPredict

Interactor 1: CLGN (O14967)
Calmegin
Gene: CLGN

Interactor 2: MET (P08581)
Hepatocyte growth factor receptor (HGF receptor) (EC 2.7.10.1) (HGF/SF receptor) (Proto-oncogene c-Met) (Scatter factor receptor) (SF receptor) (Tyrosine-protein kinase Met)
Gene: MET

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	0.50	0.549

Property	Details
Experiments	33961781, unassigned3799
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 610 Hs			1 1390
+	Hs
		471993 CALX_HUMAN (29-610): 0: 729: 56.85		MET_HUMAN (1-1390): 0: 1275: 100.00
+	Hs
		471992 CALR_HUMAN (60-456): 2.92e-129: 387: 36.00		MET_HUMAN (1-1390): 0: 1275: 100.00
+	Hs
		698405 CALX_HUMAN (29-610): 0: 729: 56.85		EPHA3_HUMAN (584-1377): 1.43e-176: 553: 18.30
+	Hs
		170709 CLGN_HUMAN (1-610): 0: 804: 100.00		PLXA3_HUMAN (381-1038): 4.99e-111: 389: 17.62
+	Hs
		698505 CALX_HUMAN (29-610): 0: 729: 56.85		PLXA3_HUMAN (381-1038): 4.99e-111: 389: 17.62
+	Hs
		641121 CALX_HUMAN (29-610): 0: 729: 56.85		FGFR2_HUMAN (1029-1379): 5.66e-105: 355: 33.15
+	Hs
		170735 CLGN_HUMAN (1-610): 0: 804: 100.00		TYRO3_HUMAN (1053-1341): 6.21e-65: 240: 41.67
+	Hs
		170555 CLGN_HUMAN (1-610): 0: 804: 100.00		PLXB2_HUMAN (365-1012): 3.15e-57: 220: 16.14
+	Hs
		170627 CLGN_HUMAN (1-610): 0: 804: 100.00		IGF1R_HUMAN (1084-1337): 2.08e-56: 217: 42.16
+	Hs
		170616 CLGN_HUMAN (1-610): 0: 804: 100.00		INSR_HUMAN (1084-1335): 3.89e-55: 213: 42.11
+	Hs
		171011 CLGN_HUMAN (1-610): 0: 804: 100.00		PLXA1_HUMAN (461-934): 1.8e-52: 205: 21.89
+	Hs
		208115 CALX_HUMAN (29-610): 0: 729: 56.85		PLXB1_HUMAN (481-1030): 2.96e-65: 246: 21.23
+	Hs
		698417 CALX_HUMAN (29-610): 0: 729: 56.85		UFO_HUMAN (1078-1333): 5.29e-66: 243: 45.90
+	Hs
		698601 CALX_HUMAN (29-610): 0: 729: 56.85		TYRO3_HUMAN (1053-1341): 6.21e-65: 240: 41.67
+	Hs
		465416 CALX_HUMAN (29-610): 0: 729: 56.85		IGF1R_HUMAN (1084-1337): 2.08e-56: 217: 42.16
+	Hs
		439649 CALX_HUMAN (29-610): 0: 729: 56.85		INSR_HUMAN (1084-1335): 3.89e-55: 213: 42.11
+	Hs
		269655 CALX_HUMAN (29-610): 0: 729: 56.85		PLXA2_HUMAN (380-1020): 4.6e-51: 201: 19.42
+	Hs
		697779 CALR_HUMAN (60-456): 2.92e-129: 387: 36.00		UFO_HUMAN (1078-1333): 5.29e-66: 243: 45.90
+	Rn
		580424 CALR_RAT (60-456): 5.11e-130: 389: 36.00		INSR_RAT (1084-1335): 3.23e-52: 204: 40.98
+	At
		146282 CALR3_ARATH (53-444): 2.41e-138: 411: 32.32		BRI1_ARATH (652-997): 7.06e-37: 154: 7.66