HitPredict

Interactor 1: P85A (P27986)
Phosphatidylinositol 3-kinase regulatory subunit alpha (PI3-kinase regulatory subunit alpha) (PI3K regulatory subunit alpha) (PtdIns-3-kinase regulatory subunit alpha) (Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha) (PI3-kinase subunit p85-alpha) (PtdIns-3-kinase regulatory subunit p85-alpha)
Gene: PIK3R1

Interactor 2: ASB11 (Q8WXH4)
Ankyrin repeat and SOCS box protein 11 (ASB-11)
Gene: ASB11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	37848033
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	SH2~SOCS_box
Common GO terms	GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 724 Hs			1 323
+	Hs
		699668 P85A_HUMAN (1-724): 0: 590: 100.00		RIPK4_HUMAN (170-321): 3.06e-24: 105: 18.71
+	Hs
		699855 P85A_HUMAN (1-724): 0: 590: 100.00		Q9H4D1_HUMAN (170-321): 5.15e-24: 104: 18.71
+	Mm
		109255 P85A_MOUSE (1-724): 0: 585: 95.99		ANK3_MOUSE (1-84): 2.19e-14: 76: 12.64
+	Hs
		1092738 RHG05_HUMAN (104-319): 3.46e-53: 201: 23.56		ASB11_HUMAN (1-323): 3.84e-85: 260: 100.00
+	Hs
		944016 P55G_HUMAN (271-723): 2.98e-104: 328: 72.31		RIPK4_HUMAN (170-321): 3.06e-24: 105: 18.71
+	Hs
		1364875 P55G_HUMAN (271-723): 2.98e-104: 328: 72.31		Q9H4D1_HUMAN (170-321): 5.15e-24: 104: 18.71
+	Hs
		914015 CHIO_HUMAN (129-305): 1.91e-54: 196: 23.76		ANKK1_HUMAN (191-321): 3.6e-30: 122: 20.90
+	Hs
		1091412 RHG21_HUMAN (78-531): 1.5e-60: 223: 12.63		ANK3_HUMAN (1-84): 2.97e-15: 78.7: 12.64
+	Hs
		1091421 RHG22_HUMAN (106-573): 3.13e-55: 203: 13.50		ANK3_HUMAN (1-84): 2.97e-15: 78.7: 12.64
+	Hs
		586985 CHIN_HUMAN (580-696): 2.15e-12: 71.9: 16.81		ANKK1_HUMAN (191-321): 3.6e-30: 122: 20.90
+	Dm
		119605 M9PAY7_DROME (322-428): 1.99e-13: 71.4: 27.78		ANKHM_DROME (200-323): 6.72e-20: 92.6: 18.05