HitPredict

Interactor 1: FAK1 (P34152)
Focal adhesion kinase 1 (FADK 1) (EC 2.7.10.2) (Focal adhesion kinase-related nonkinase) (FRNK) (Protein-tyrosine kinase 2) (p125FAK) (pp125FAK)
Gene: Ptk2

Interactor 2: PAXI (Q8VI36)
Paxillin
Gene: Pxn

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.928

The method score is based on:

Property Details
Experiments 21289086, 15494312, 15138291, 20308429, 10931187, 16298995
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Focal_AT~Paxillin
Common GO terms GO:0005178 - integrin binding
GO:0005925 - focal adhesion
GO:0005938 - cell cortex
GO:0007229 - integrin-mediated signaling pathway
GO:0008360 - regulation of cell shape
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1052
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1 591
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024