HitPredict

Interactor 1: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Interactor 2: PAR3L (Q8TEW8)
Partitioning defective 3 homolog B (Amyotrophic lateral sclerosis 2 chromosomal region candidate gene 19 protein) (PAR3-beta) (Partitioning defective 3-like protein) (PAR3-L protein)
Gene: PARD3B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	36976175
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~fn3, PDZ~SAM_1
Common GO terms	GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 976 Hs			1 1205
+	Hs
		710389 EPHA2_HUMAN (1-976): 0: 1124: 100.00		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		1147390 EPHA7_HUMAN (4-974): 0: 1120: 50.15		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		931873 EPHA5_HUMAN (11-976): 0: 1115: 51.34		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		932104 EPHA4_HUMAN (1-974): 0: 1110: 50.35		PARD3_HUMAN (1-1180): 6.42e-123: 414: 35.12
+	Hs
		710208 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Hs
		1091501 EPHA7_HUMAN (4-974): 0: 1120: 50.15		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Hs
		931842 EPHA5_HUMAN (11-976): 0: 1115: 51.34		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Hs
		932062 EPHA4_HUMAN (1-974): 0: 1110: 50.35		DLG1_HUMAN (47-742): 1.47e-49: 192: 10.71
+	Hs
		1147388 EPHA7_HUMAN (4-974): 0: 1120: 50.15		LNX1_HUMAN (289-749): 7.23e-31: 132: 14.89
+	Hs
		1147375 EPHA7_HUMAN (4-974): 0: 1120: 50.15		LNX2_HUMAN (272-749): 4.45e-29: 127: 13.96
+	Hs
		932103 EPHA4_HUMAN (1-974): 0: 1110: 50.35		LNX1_HUMAN (289-749): 7.23e-31: 132: 14.89
+	Hs
		710408 EPHA2_HUMAN (1-976): 0: 1124: 100.00		DLG3_HUMAN (47-389): 2.17e-21: 102: 12.83
+	Hs
		710588 EPHA2_HUMAN (1-976): 0: 1124: 100.00		GRIP1_HUMAN (166-507): 1.75e-20: 100: 11.50
+	Hs
		710205 EPHA2_HUMAN (1-976): 0: 1124: 100.00		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Hs
		1090129 EPHA7_HUMAN (4-974): 0: 1120: 50.15		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Hs
		931840 EPHA5_HUMAN (11-976): 0: 1115: 51.34		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Hs
		710238 EPHA2_HUMAN (1-976): 0: 1124: 100.00		SCRIB_HUMAN (123-285): 3.84e-09: 63.5: 15.48
+	Hs
		932061 EPHA4_HUMAN (1-974): 0: 1110: 50.35		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95
+	Hs
		1122235 EPHA7_HUMAN (4-974): 0: 1120: 50.15		SCRIB_HUMAN (123-285): 3.84e-09: 63.5: 15.48
+	Hs
		710622 EPHA3_HUMAN (24-976): 0: 1096: 50.98		PTN13_HUMAN (141-313): 9.3e-13: 75.4: 16.95