HitPredict

Interactor 1: SHC1 (P29353)
SHC-transforming protein 1 (SHC-transforming protein 3) (SHC-transforming protein A) (Src homology 2 domain-containing-transforming protein C1) (SH2 domain protein C1)
Gene: SHC1

Interactor 2: K1C9 (P35527)
Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)
Gene: KRT9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19380743
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 583 Hs			1 623
+	Hs
		566243 SHC1_HUMAN (1-583): 0: 529: 100.00		K1C13_HUMAN (141-478): 3.34e-150: 443: 53.25
+	Hs
		385057 SHC1_HUMAN (1-583): 0: 529: 100.00		K1C14_HUMAN (151-484): 5.31e-149: 440: 55.39
+	Hs
		476272 SHC1_HUMAN (1-583): 0: 529: 100.00		K1C16_HUMAN (149-478): 1.73e-141: 421: 54.85
+	Hs
		711316 SHC1_HUMAN (1-583): 0: 529: 100.00		K1C17_HUMAN (84-476): 3.4e-139: 414: 49.36
+	Hs
		300448 SHC3_HUMAN (6-582): 8.25e-126: 384: 45.81		KRT34_HUMAN (107-491): 1.26e-144: 426: 36.90
+	Hs
		1230175 SHC3_HUMAN (6-582): 8.25e-126: 384: 45.81		K1C40_HUMAN (80-486): 5.11e-140: 416: 35.12
+	Hs
		566335 SHC1_HUMAN (1-583): 0: 529: 100.00		K2C5_HUMAN (1-468): 2.36e-72: 245: 23.14
+	Hs
		385240 SHC1_HUMAN (1-583): 0: 529: 100.00		K2C6A_HUMAN (2-484): 9.74e-70: 237: 23.12
+	Hs
		1146077 SHC3_HUMAN (6-582): 8.25e-126: 384: 45.81		K1H1_HUMAN (103-479): 3.45e-104: 323: 37.14
+	Hs
		1127668 SHC3_HUMAN (6-582): 8.25e-126: 384: 45.81		KT33B_HUMAN (107-493): 8.29e-101: 314: 36.18
+	Hs
		227252 SHC3_HUMAN (6-582): 8.25e-126: 384: 45.81		KRT86_HUMAN (37-465): 1.11e-81: 267: 22.33
+	Hs
		300450 ANS1A_HUMAN (63-393): 1.28e-60: 219: 19.36		KRT34_HUMAN (107-491): 1.26e-144: 426: 36.90
+	Hs
		300371 Q49AR9_HUMAN (40-425): 3.65e-47: 175: 17.22		KRT34_HUMAN (107-491): 1.26e-144: 426: 36.90
+	Hs
		1146079 ANS1A_HUMAN (63-393): 1.28e-60: 219: 19.36		K1H1_HUMAN (103-479): 3.45e-104: 323: 37.14
+	Hs
		1145959 Q49AR9_HUMAN (40-425): 3.65e-47: 175: 17.22		K1H1_HUMAN (103-479): 3.45e-104: 323: 37.14
+	Hs
		341824 ANS1A_HUMAN (63-393): 1.28e-60: 219: 19.36		K2C75_HUMAN (1-551): 2.22e-83: 273: 22.02
+	Hs
		1007497 ANS1A_HUMAN (63-393): 1.28e-60: 219: 19.36		KRT83_HUMAN (33-536): 2.22e-83: 272: 21.78
+	Hs
		341781 Q49AR9_HUMAN (40-425): 3.65e-47: 175: 17.22		K2C75_HUMAN (1-551): 2.22e-83: 273: 22.02
+	Hs
		1007482 Q49AR9_HUMAN (40-425): 3.65e-47: 175: 17.22		KRT83_HUMAN (33-536): 2.22e-83: 272: 21.78
+	Hs
		1363728 SHC3_HUMAN (6-582): 8.25e-126: 384: 45.81		KRT35_HUMAN (212-556): 9.35e-09: 59.9: 8.88