Protein: INGR1
Interferon gamma receptor 1 (IFN-gamma receptor 1) (IFN-gamma-R1) (CDw119) (Interferon gamma receptor alpha-chain) (IFN-gamma-R-alpha) (CD antigen CD119)

Gene: INGR1, IFNGR1
Organism: Homo sapiens
Interactions: 87
UniProt ID: P15260

Gene Ontology (top 5):
GO:0001774 - microglial cell activation
GO:0004896 - cytokine receptor activity
GO:0004906 - type II interferon receptor activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352913

IFNG
Interferon gamma

7

1

Small-scale

0.970

High

546493

NOTC3
Neurogenic locus notch homolog protein 3

2

1

High-throughput

0.811

High

546439

INGR2
Interferon gamma receptor 2

2

11

Small-scale

0.754

High

546441

STAT1
Signal transducer and activator of transcription 1-alpha/beta

6

14

Small-scale

0.717

High

546433

JAK1
Tyrosine-protein kinase JAK1

4

18

Small-scale

0.700

High

409495

HEPS
Serine protease hepsin

1

1

High-throughput

0.691

High

546430

INAR1
Interferon alpha/beta receptor 1

1

15

High-throughput

0.691

High

546477

SL9A6
Sodium/hydrogen exchanger 6

4

0

High-throughput

0.669

High

154301

TR10B
Tumor necrosis factor receptor superfamily member 10B

3

4

High-throughput

0.667

High

546465

RHOU
Rho-related GTP-binding protein RhoU

3

9

High-throughput

0.667

High

546478

RUSF1
RUS family member 1

3

1

High-throughput

0.665

High

507827

FGFR1
Fibroblast growth factor receptor 1

2

3

High-throughput

0.628

High

546437

BMR1A
Bone morphogenetic protein receptor type-1A

2

7

High-throughput

0.628

High

546461

CC50B
Cell cycle control protein 50B

2

1

High-throughput

0.628

High

546467

LRP10
Low-density lipoprotein receptor-related protein 10

2

3

High-throughput

0.628

High

546475

RAE1E
Retinoic acid early transcript 1E

2

4

High-throughput

0.628

High

546442

MUC18
Cell surface glycoprotein MUC18

1

1

High-throughput

0.618

High

546463

I20RB
Interleukin-20 receptor subunit beta

1

11

High-throughput

0.618

High

546491

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

3

1

Small-scale

0.609

High

546471

AGRG5
Adhesion G-protein coupled receptor G5

2

0

High-throughput

0.602

High

546486

CD320
CD320 antigen

2

0

High-throughput

0.602

High

238344

JAK2
Tyrosine-protein kinase JAK2

2

18

Small-scale

0.584

High

349850

RASK
GTPase KRas

2

5

High-throughput

0.584

High

546449

RHOB
Rho-related GTP-binding protein RhoB

2

7

High-throughput

0.584

High

546456

AQP6
Aquaporin-6

2

0

High-throughput

0.580

High

546457

STIM1
Stromal interaction molecule 1

2

0

High-throughput

0.580

High

546481

TM237
Transmembrane protein 237

2

0

High-throughput

0.580

High

546487

TM100
Transmembrane protein 100

2

0

High-throughput

0.580

High

546489

NINJ2
Ninjurin-2

2

0

High-throughput

0.580

High

546482

NFIP1
NEDD4 family-interacting protein 1

2

2

High-throughput

0.574

High

522745

SRC
Proto-oncogene tyrosine-protein kinase Src

1

1

High-throughput

0.536

High

546435

CALX
Calnexin

1

1

High-throughput

0.536

High

546436

RYK
Tyrosine-protein kinase RYK

1

7

High-throughput

0.536

High

546444

CTXN1
Cortexin-1

1

1

High-throughput

0.536

High

546454

NKG2E
NKG2-E type II integral membrane protein

1

2

High-throughput

0.536

High

546466

KCNKI
Potassium channel subfamily K member 18

1

1

High-throughput

0.536

High

546473

RN149
E3 ubiquitin-protein ligase RNF149

1

1

High-throughput

0.536

High

546485

CRLF2
Cytokine receptor-like factor 2

1

3

High-throughput

0.536

High

546494

EDAR
Tumor necrosis factor receptor superfamily member EDAR

1

1

High-throughput

0.536

High

500983

IRF1
Interferon regulatory factor 1

1

3

Small-scale

0.534

High

132736

SDCB1
Syntenin-1

1

0

High-throughput

0.513

High

536562

HCLS1
Hematopoietic lineage cell-specific protein

1

0

High-throughput

0.513

High

546451

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

546468

T200A
Transmembrane protein 200A

1

0

High-throughput

0.513

High

546470

NRSN1
Neurensin-1

1

0

High-throughput

0.513

High

546474

MARH1
E3 ubiquitin-protein ligase MARCHF1

1

0

High-throughput

0.513

High

546480

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

546479

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

1

2

High-throughput

0.489

High

178383

STX7
Syntaxin-7

1

2

High-throughput

0.479

High

181786

SOCS1
Suppressor of cytokine signaling 1

1

8

Small-scale

0.479

High

204995

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

237782

TSN3
Tetraspanin-3

1

1

High-throughput

0.479

High

348494

RASN
GTPase NRas

1

4

High-throughput

0.479

High

349102

RASH
GTPase HRas

1

4

High-throughput

0.479

High

436142

RHOC
Rho-related GTP-binding protein RhoC

1

6

High-throughput

0.479

High

546429

RHOQ
Rho-related GTP-binding protein RhoQ

1

8

High-throughput

0.479

High

546443

RND2
Rho-related GTP-binding protein RhoN

1

7

High-throughput

0.479

High

546445

RAC3
Ras-related C3 botulinum toxin substrate 3

1

7

High-throughput

0.479

High

546446

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.479

High

546447

RHOA
Transforming protein RhoA

1

6

High-throughput

0.479

High

546450

RAC1
Ras-related C3 botulinum toxin substrate 1

1

7

High-throughput

0.479

High

546452

RHOG
Rho-related GTP-binding protein RhoG

1

6

High-throughput

0.479

High

546455

STX4
Syntaxin-4

1

2

High-throughput

0.479

High

546459

RHOH
Rho-related GTP-binding protein RhoH

1

8

High-throughput

0.479

High

546469

PARP9
Protein mono-ADP-ribosyltransferase PARP9

1

1

Small-scale

0.479

High

546483

RHOJ
Rho-related GTP-binding protein RhoJ

1

8

High-throughput

0.479

High

546431

EGR1
Early growth response protein 1

1

0

High-throughput

0.458

High

546432

NFKB1
Nuclear factor NF-kappa-B p105 subunit

1

0

High-throughput

0.458

High

546434

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

546453

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

546460

OCLN
Occludin

1

0

High-throughput

0.458

High

546472

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.458

High

546488

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

546490

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

546438

TGFR2
TGF-beta receptor type-2

1

7

High-throughput

0.445

High

536465

IRF2
Interferon regulatory factor 2

1

3

Small-scale

0.437

High

546440

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.437

High

546495

CHIP
E3 ubiquitin-protein ligase CHIP

1

3

Small-scale

0.437

High

546458

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

0

High-throughput

0.426

High

546448

RB11A
Ras-related protein Rab-11A

2

0

High-throughput

0.305

High

546484

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.279

Low

546492

FBX2
F-box only protein 2

1

0

High-throughput

0.279

Low

132414

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

0

High-throughput

0.249

Low

541503

I23O1
Indoleamine 2,3-dioxygenase 1

1

0

Small-scale

0.249

Low

546462

SLX4I
Protein SLX4IP

1

0

Small-scale

0.249

Low

546464

H32
Histone H3.2

1

0

Small-scale

0.249

Low

546476

DTX3L
E3 ubiquitin-protein ligase DTX3L

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024