Interactor 1: CRLF1 (O75462)
Cytokine receptor-like factor 1 (Cytokine-like factor 1) (CLF-1) (ZcytoR5)
Gene: CRLF1
Interactor 2: CNTFR (P26992)
Ciliary neurotrophic factor receptor subunit alpha (CNTF receptor subunit alpha) (CNTFR-alpha)
Gene: CNTFR
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.46 | 1.00 | 0.681 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 26858303 |
| Identification Methods | surface plasmon resonance |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | EpoR_lig-bind~fn3, fn3~fn3 |
| Common GO terms | GO:0008284 - positive regulation of cell population proliferation GO:0009897 - external side of plasma membrane GO:0019955 - cytokine binding GO:0043524 - negative regulation of neuron apoptotic process GO:2000672 - negative regulation of motor neuron apoptotic process |
| Homologous interactions | 19 |
Homologous interactions
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Service provided by Combinatics, Japan
Last updated: 11Aug2025
