Interactor 1: I12R2 (P97378)
Interleukin-12 receptor subunit beta-2 (IL-12 receptor subunit beta-2) (IL-12R subunit beta-2) (IL-12R-beta-2) (IL-12RB2)
Gene: Il12rb2

Interactor 2: IL6RB (Q00560)
Interleukin-6 receptor subunit beta (IL-6 receptor subunit beta) (IL-6R subunit beta) (IL-6R-beta) (IL-6RB) (Interleukin-6 signal transducer) (Membrane glycoprotein 130) (gp130) (Oncostatin-M receptor subunit alpha) (CD antigen CD130)
Gene: Il6st

Species: Mus musculus

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 22306691
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains fn3~fn3, IL6Ra-bind~fn3, Lep_receptor_Ig~fn3, IL6Ra-bind~Lep_receptor_Ig
Common GO terms GO:0009897 - external side of plasma membrane
GO:0015026 - coreceptor activity
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 874
Mm

1 917
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Mm
+ Mm

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Last updated: 11Aug2025