HitPredict

Interactor 1: RUXGL (A8MWD9)
Putative small nuclear ribonucleoprotein G-like protein 15
Gene: SNRPGP15

Interactor 2: PRP8 (Q6P2Q9)
Pre-mRNA-processing-splicing factor 8 (220 kDa U5 snRNP-specific protein) (PRP8 homolog) (Splicing factor Prp8) (p220)
Gene: PRPF8

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	28514442
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	LSM~PRP8_domainIV
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005682 - U5 snRNP GO:0071013 - catalytic step 2 spliceosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 76 Hs			1 2335
+	Hs
		974146 RUXG_HUMAN (1-76): 5.36e-30: 102: 94.74		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		1241840 LSM7_HUMAN (3-76): 1.32e-24: 89.8: 31.71		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		991203 RSMN_HUMAN (1-70): 9.36e-23: 88.6: 21.25		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		973950 RUXF_HUMAN (5-73): 9.09e-24: 87.1: 26.09		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		574326 RSMB_HUMAN (1-70): 5.03e-22: 86.7: 21.25		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Hs
		344548 LSM8_HUMAN (6-75): 5.3e-21: 80.2: 22.97		PRP8_HUMAN (1-2335): 0: 4632: 100.00
+	Sc
		751748 RUXG_YEAST (7-76): 5.35e-22: 82.3: 50.69		PRP8_YEAST (23-2335): 0: 3828: 62.28
+	Sc
		751770 RUXF_YEAST (5-73): 2.83e-21: 80.6: 24.29		PRP8_YEAST (23-2335): 0: 3828: 62.28
+	Sc
		751768 LSM7_YEAST (3-75): 1.41e-18: 74.8: 30.95		PRP8_YEAST (23-2335): 0: 3828: 62.28
+	Sc
		751771 LSM3_YEAST (4-72): 4.34e-10: 52.6: 28.57		PRP8_YEAST (23-2335): 0: 3828: 62.28