HitPredict

Interactor 1: PSB5 (P30655)
Probable proteasome subunit beta type-5 (EC 3.4.25.1) (Macropain subunit pts1) (Multicatalytic endopeptidase complex subunit pts1) (Proteasome component pts1)
Gene: pts1

Interactor 2: RPN1 (P87048)
26S proteasome regulatory subunit rpn1 (19S regulatory cap region of 26S protease subunit 2) (Proteasome non-ATPase subunit mts4)
Gene: RPN1

Species: Schizosaccharomyces pombe 972h-

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28784663
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 272 Sp			1 891
+	Sp
		1017853 PSA5_SCHPO (20-263): 2.05e-89: 267: 16.47		RPN1_SCHPO (1-891): 0: 1228: 100.00
+	Hs
		700622 PSA5_HUMAN (20-260): 1.2e-87: 262: 15.94		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Sp
		1017837 PSA3_SCHPO (24-266): 2.13e-83: 252: 13.78		RPN1_SCHPO (1-891): 0: 1228: 100.00
+	Hs
		700459 PSB8_HUMAN (10-265): 6.91e-85: 256: 49.61		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		681155 PSA2_HUMAN (23-261): 8.13e-84: 252: 13.17		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		701143 PSB5_HUMAN (16-261): 7.04e-83: 251: 53.25		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Hs
		681635 PSA4_HUMAN (24-257): 1.16e-82: 250: 17.62		PSMD2_HUMAN (1-885): 0: 1224: 47.36
+	Dm
		1376944 PSA5_DROME (20-261): 2.31e-86: 259: 18.11		Q9VW54_DROME (41-885): 0: 1064: 46.89
+	Sc
		721256 PSB5_YEAST (7-270): 7.38e-84: 254: 61.89		RPN1_YEAST (50-885): 0: 901: 39.42
+	Hs
		700715 PSA5_HUMAN (20-260): 1.2e-87: 262: 15.94		PSMD1_HUMAN (141-826): 6.12e-171: 522: 19.43
+	Hs
		681219 PSA2_HUMAN (23-261): 8.13e-84: 252: 13.17		PSMD1_HUMAN (141-826): 6.12e-171: 522: 19.43
+	Hs
		701210 PSB5_HUMAN (16-261): 7.04e-83: 251: 53.25		PSMD1_HUMAN (141-826): 6.12e-171: 522: 19.43
+	Hs
		681704 PSA4_HUMAN (24-257): 1.16e-82: 250: 17.62		PSMD1_HUMAN (141-826): 6.12e-171: 522: 19.43
+	Sc
		721239 PSB5_YEAST (7-270): 7.38e-84: 254: 61.89		RPN2_YEAST (60-822): 4.17e-145: 455: 18.37
+	Dm
		1376919 PSA5_DROME (20-261): 2.31e-86: 259: 18.11		PSMD1_DROME (370-819): 2.86e-141: 447: 21.91
+	Hs
		688 PSA5_HUMAN (20-260): 1.2e-87: 262: 15.94		A0A087WW66_HUMAN (141-826): 6.96e-140: 440: 18.87
+	Dm
		1264681 Q7K148_DROME (8-263): 2.92e-82: 250: 49.22		PSMD1_DROME (370-819): 2.86e-141: 447: 21.91
+	Hs
		685 PSA2_HUMAN (23-261): 8.13e-84: 252: 13.17		A0A087WW66_HUMAN (141-826): 6.96e-140: 440: 18.87
+	Hs
		690 PSB5_HUMAN (16-261): 7.04e-83: 251: 53.25		A0A087WW66_HUMAN (141-826): 6.96e-140: 440: 18.87
+	Hs
		687 PSA4_HUMAN (24-257): 1.16e-82: 250: 17.62		A0A087WW66_HUMAN (141-826): 6.96e-140: 440: 18.87