Interactor 1: SC6A4 (P31645)
Sodium-dependent serotonin transporter (SERT) (5HT transporter) (5HTT) (Solute carrier family 6 member 4)
Gene: SLC6A4

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.55 0.60 0.578

The method score is based on:

Property Details
Experiments 24878716
Identification Methods pull down, affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005886 - plasma membrane
GO:0017075 - syntaxin-1 binding
GO:0043005 - neuron projection
GO:0045202 - synapse
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 630
Hs

1 116
+ Rn
+ Mm
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024