HitPredict

Interactor 1: RENT1 (P30771)
ATP-dependent helicase NAM7 (EC 3.6.4.12) (EC 3.6.4.13) (Nonsense-mediated mRNA decay protein 1) (Nuclear accommodation of mitochondria 7 protein) (Up-frameshift suppressor 1)
Gene: NAM7

Interactor 2: LSM1 (P47017)
LSM1-LSM7 complex subunit LSM1 (SPB8 protein)
Gene: LSM1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.79	0.60	0.692

Property	Details
Experiments	11805826, 30275269, 39437715, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology, protein complementation assay
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003729 - mRNA binding GO:0005737 - cytoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 971 Sc			1 172
+	Sc
		721648 RENT1_YEAST (1-971): 0: 1317: 100.00		LSM7_YEAST (8-119): 4.94e-26: 97.5: 27.97
+	Sc
		721650 RENT1_YEAST (1-971): 0: 1317: 100.00		LSM3_YEAST (46-120): 1.16e-19: 80.2: 29.87
+	Hs
		344562 RENT1_HUMAN (37-902): 0: 1142: 53.69		LSM8_HUMAN (43-135): 8.61e-29: 104: 32.98
+	Hs
		991219 RENT1_HUMAN (37-902): 0: 1142: 53.69		RSMN_HUMAN (42-118): 8.3e-24: 95.1: 28.24
+	Hs
		574402 RENT1_HUMAN (37-902): 0: 1142: 53.69		RSMB_HUMAN (42-118): 3.02e-23: 93.6: 28.24
+	Sc
		865276 SEN1_YEAST (222-879): 1.13e-156: 512: 23.04		LSM8_YEAST (43-150): 4.49e-21: 84.7: 18.52
+	Sc
		817143 SEN1_YEAST (222-879): 1.13e-156: 512: 23.04		RSMB_YEAST (35-153): 5.8e-20: 84: 21.32
+	Hs
		344516 SMBP2_HUMAN (292-893): 9.55e-155: 484: 25.84		LSM8_HUMAN (43-135): 8.61e-29: 104: 32.98