HitPredict

Interactor 1: B3KSH4 (B3KSH4)
Huntingtin interacting protein 2, isoform CRA_a (cDNA FLJ36214 fis, clone THYMU2000672, highly similar to Ubiquitin-conjugating enzyme E2-25 kDa)
Gene: HIP2

Interactor 2: RN167 (Q9H6Y7)
E3 ubiquitin-protein ligase RNF167 (EC 2.3.2.27) (RING finger protein 167)
Gene: RNF167

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.34	0.80	0.528

Property	Details
Experiments	19549727
Identification Methods	two hybrid array
Interaction Type	physical association

Property	Details
Interacting Pfam domains	UQ_con~zf-RING_2
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 97 Hs			1 350
+	Hs
		896377 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RN167_HUMAN (1-333): 6.01e-92: 280: 100.00
+	Hs
		919862 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN167_HUMAN (1-333): 6.01e-92: 280: 100.00
+	Hs
		895913 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN167_HUMAN (1-333): 6.01e-92: 280: 100.00
+	Hs
		207553 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF13_HUMAN (17-347): 9.34e-78: 245: 47.43
+	Hs
		207551 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RNF13_HUMAN (17-347): 9.34e-78: 245: 47.43
+	Hs
		919903 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN150_HUMAN (40-330): 1.57e-58: 197: 24.60
+	Hs
		919789 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN149_HUMAN (33-305): 1.09e-57: 193: 20.47
+	Hs
		895858 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN128_HUMAN (17-341): 1.12e-57: 194: 20.56
+	Hs
		895848 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RN149_HUMAN (33-305): 1.09e-57: 193: 20.47
+	Hs
		919772 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		GOLI_HUMAN (43-345): 8.96e-55: 186: 21.41
+	Hs
		919802 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		ZNRF4_HUMAN (8-302): 1.38e-53: 184: 37.01
+	Hs
		895837 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		GOLI_HUMAN (43-345): 8.96e-55: 186: 21.41
+	Hs
		895860 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		ZNRF4_HUMAN (8-302): 1.38e-53: 184: 37.01
+	Hs
		919752 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF43_HUMAN (39-344): 3.57e-43: 160: 20.85
+	Hs
		895814 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		RNF43_HUMAN (39-344): 3.57e-43: 160: 20.85
+	Hs
		896385 UBE2K_HUMAN (1-97): 1.07e-33: 116: 100.00		RNF12_HUMAN (175-278): 2.8e-28: 117: 32.69
+	Hs
		919877 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RNF12_HUMAN (175-278): 2.8e-28: 117: 32.69
+	Hs
		919766 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		SYVN1_HUMAN (104-294): 1.78e-27: 115: 17.35
+	Hs
		895831 UB2D3_HUMAN (1-51): 6.77e-29: 102: 35.29		SYVN1_HUMAN (104-294): 1.78e-27: 115: 17.35
+	Hs
		919865 UB2D2_HUMAN (1-51): 4.95e-30: 105: 39.22		RN122_HUMAN (168-275): 4.82e-27: 106: 29.09