HitPredict

Interactor 1: SOX5 (P35711)
Transcription factor SOX-5
Gene: SOX5

Interactor 2: RCOR1 (Q9UKL0)
REST corepressor 1 (Protein CoREST)
Gene: RCOR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 763 Hs			1 485
+	Hs
		727817 SOX5_HUMAN (1-763): 0: 611: 100.00		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		727796 SOX5_HUMAN (1-763): 0: 611: 100.00		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		727940 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		727935 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		RCOR3_HUMAN (105-480): 6.86e-123: 369: 63.08
+	Hs
		727915 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		727860 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		261421 SOX5_HUMAN (1-763): 0: 611: 100.00		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		727832 SOX5_HUMAN (1-763): 0: 611: 100.00		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		1300986 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		883318 SOX8_HUMAN (551-633): 8.17e-37: 146: 48.19		RCOR1_HUMAN (1-485): 5.94e-148: 433: 100.00
+	Hs
		261422 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86
+	Hs
		727951 SOX6_HUMAN (14-763): 6.99e-144: 444: 56.44		NCOR2_HUMAN (194-380): 9.4e-09: 60.4: 12.11
+	Hs
		1300922 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		MTA3_HUMAN (80-485): 5.88e-92: 293: 17.42
+	Hs
		1031932 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		818012 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MTA1_HUMAN (81-410): 5.09e-71: 241: 16.03
+	Hs
		296107 CIC_HUMAN (305-752): 1.22e-35: 147: 15.96		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		295961 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MTA2_HUMAN (85-446): 1.69e-64: 222: 16.67
+	Hs
		818811 SOX9_HUMAN (463-700): 7.73e-45: 170: 26.86		MDEAS_HUMAN (105-381): 6.79e-46: 173: 16.67
+	Hs
		818169 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		MDEAS_HUMAN (105-381): 6.79e-46: 173: 16.67
+	Hs
		261435 SOX2_HUMAN (520-642): 2.65e-36: 141: 38.10		NCOR1_HUMAN (194-465): 5.18e-11: 67.4: 12.86