Interactor 1: NTRK1 (P35739)
High affinity nerve growth factor receptor (EC 2.7.10.1) (Neurotrophic tyrosine kinase receptor type 1) (Slow nerve growth factor receptor) (p140-TrkA) (Trk-A)
Gene: NTRK1
Interactor 2: GRB2 (P62994)
Growth factor receptor-bound protein 2 (Adapter protein GRB2) (Protein Ash) (SH2/SH3 adapter GRB2)
Gene: GRB2
Species: Rattus norvegicus
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.50 | 1.00 | 0.708 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10748052 |
| Identification Methods | pull down, two hybrid, coimmunoprecipitation |
| Interaction Type | association, physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | LRR_8~SH2, PK_Tyr_Ser-Thr~SH2, PK_Tyr_Ser-Thr~SH3_1 |
| Common GO terms | GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0032991 - protein-containing complex |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
