HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: GAB1 (Q13480)
GRB2-associated-binding protein 1 (GRB2-associated binder 1) (Growth factor receptor bound protein 2-associated protein 1)
Gene: GAB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 694
+	Hs
		971489 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		GAB1_HUMAN (1-694): 6.33e-173: 512: 100.00
+	Hs
		972145 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		GAB2_HUMAN (3-691): 1.85e-144: 438: 38.73
+	Hs
		730363 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		GAB2_HUMAN (3-691): 1.85e-144: 438: 38.73
+	Hs
		971965 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		DOCK9_HUMAN (3-654): 1.48e-127: 419: 14.68
+	Hs
		730213 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		DOCK9_HUMAN (3-654): 1.48e-127: 419: 14.68
+	Mm
		972221 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		Q3ZB59_MOUSE (3-691): 6.68e-131: 403: 38.05
+	Mm
		990071 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		GAB2_MOUSE (3-691): 3.12e-131: 404: 38.05
+	Mm
		989962 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		Q3ZB59_MOUSE (3-691): 6.68e-131: 403: 38.05
+	Hs
		971603 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		DOC11_HUMAN (3-682): 1.46e-118: 393: 13.21
+	Hs
		729900 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		DOC11_HUMAN (3-682): 1.46e-118: 393: 13.21
+	Hs
		66040 1433Z_HUMAN (3-244): 1.49e-141: 398: 87.60		A6NIW2_HUMAN (3-682): 1.46e-118: 393: 13.21
+	Hs
		972012 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		730255 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		PKHA5_HUMAN (5-476): 3.42e-64: 232: 12.37
+	Hs
		971646 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		PKHA7_HUMAN (5-485): 2.19e-62: 227: 11.88
+	Hs
		729946 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		PKHA7_HUMAN (5-485): 2.19e-62: 227: 11.88
+	Mm
		990004 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		CNKR2_MOUSE (7-405): 2.21e-57: 212: 15.94
+	Hs
		972013 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		PKHA2_HUMAN (2-194): 4.15e-35: 140: 20.77
+	Hs
		730256 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		PKHA2_HUMAN (2-194): 4.15e-35: 140: 20.77
+	Hs
		972015 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49
+	Hs
		730257 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		PKHA1_HUMAN (6-156): 1.01e-32: 132: 25.49