HitPredict

Interactor 1: 1433B (P31946)
14-3-3 protein beta/alpha (Protein 1054) (Protein kinase C inhibitor protein 1) (KCIP-1) [Cleaved into: 14-3-3 protein beta/alpha, N-terminally processed]
Gene: YWHAB

Interactor 2: MRCKG (Q6DT37)
Serine/threonine-protein kinase MRCK gamma (EC 2.7.11.1) (CDC42-binding protein kinase gamma) (DMPK-like gamma) (Myotonic dystrophy kinase-related CDC42-binding kinase gamma) (MRCK gamma) (MRCKG) (Myotonic dystrophy protein kinase-like gamma) (Myotonic dystrophy protein kinase-like alpha)
Gene: CDC42BPG

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	unassigned3799
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	14-3-3~C1_1
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 246 Hs			1 1551
+	Hs
		971623 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MRCKA_HUMAN (2-1539): 0: 1280: 43.45
+	Hs
		729924 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MRCKA_HUMAN (2-1539): 0: 1280: 43.45
+	Hs
		971777 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MINK1_HUMAN (47-1344): 0: 616: 14.96
+	Hs
		730052 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MINK1_HUMAN (47-1344): 0: 616: 14.96
+	Hs
		692031 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MARK3_HUMAN (17-767): 5.56e-149: 475: 16.23
+	Hs
		692003 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MARK3_HUMAN (17-767): 5.56e-149: 475: 16.23
+	Mm
		972206 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		MARK3_MOUSE (17-767): 1.88e-148: 474: 16.36
+	Hs
		729994 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		TAOK1_HUMAN (45-878): 8.72e-144: 469: 16.25
+	Mm
		989952 1433Z_MOUSE (3-244): 3.15e-142: 399: 88.02		MARK3_MOUSE (17-767): 1.88e-148: 474: 16.36
+	Hs
		971985 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		SIK2_HUMAN (60-847): 1.28e-138: 453: 16.26
+	Hs
		730227 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		SIK2_HUMAN (60-847): 1.28e-138: 453: 16.26
+	Mm
		972253 1433E_MOUSE (3-243): 4.41e-144: 405: 65.43		TAOK2_MOUSE (45-887): 3.34e-135: 452: 16.36
+	Xl
		237423 O57468_XENLA (4-243): 2.72e-143: 402: 66.12		Q804T2_XENLA (17-767): 1.64e-141: 454: 15.44
+	Hs
		972078 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		MARK1_HUMAN (12-767): 1.83e-138: 448: 16.01
+	Hs
		730302 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		MARK1_HUMAN (12-767): 1.83e-138: 448: 16.01
+	Hs
		605628 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		KAPCA_HUMAN (43-371): 9.61e-129: 406: 33.14
+	Hs
		972153 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ST38L_HUMAN (23-398): 1.81e-124: 399: 38.78
+	Hs
		730371 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		ST38L_HUMAN (23-398): 1.81e-124: 399: 38.78
+	Hs
		729856 1433B_HUMAN (1-246): 3.49e-144: 404: 100.00		STK38_HUMAN (2-398): 6.79e-123: 394: 38.11
+	Hs
		971486 1433E_HUMAN (3-243): 4.41e-144: 405: 65.43		ROCK1_HUMAN (359-918): 4.04e-15: 83.4: 10.79