HitPredict

Interactor 1: AP1B1 (P36000)
AP-1 complex subunit beta-1 (Beta-1-adaptin) (Clathrin assembly protein complex 1 beta-1 large chain) (Clathrin assembly protein large beta-1 chain)
Gene: APL2

Interactor 2: AP1M1 (Q00776)
AP-1 complex subunit mu-1-I (Clathrin assembly protein complex 1 mu-1-I medium chain) (Clathrin coat assembly protein AP54) (Clathrin coat-associated protein AP54) (Golgi adaptor AP-1 54 kDa protein) (HA1 54 kDa subunit) (Mu(1)-adaptin) (Mu1-I-adaptin)
Gene: APM1

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 1.00 0.984

The method score is based on:

Property Details
Experiments 17892321, 11283351, 10688190, 10564262, 11805837, 11805826, 16429126, 18719252, 22940862, 16554755, 18467557, 37968396
Identification Methods anti tag coimmunoprecipitation, two hybrid pooling approach, two hybrid, coimmunoprecipitation, tandem affinity purification, affinity chromatography technology, protein complementation assay, dihydrofolate reductase reconstruction
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adaptin_N, Adaptin_N~Clat_adaptor_s
Common GO terms GO:0005829 - cytosol
GO:0005905 - clathrin-coated pit
GO:0006886 - intracellular protein transport
GO:0006896 - Golgi to vacuole transport
GO:0016192 - vesicle-mediated transport
and 2 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 726
Sc

1 475
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Last updated: 15 Jul 2024