HitPredict

Interactor 1: 1433S (P31947)
14-3-3 protein sigma (Epithelial cell marker protein 1) (Stratifin)
Gene: SFN

Interactor 2: LMTK2 (Q8IWU2)
Serine/threonine-protein kinase LMTK2 (EC 2.7.11.1) (Apoptosis-associated tyrosine kinase 2) (Brain-enriched kinase) (hBREK) (CDK5/p35-regulated kinase) (CPRK) (Kinase/phosphatase/inhibitor 2) (Lemur tyrosine kinase 2) (Serine/threonine-protein kinase KPI-2)
Gene: LMTK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	36931259
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	14-3-3~PK_Tyr_Ser-Thr
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 248 Hs			1 1503
+	Hs
		730766 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		MINK1_HUMAN (113-1179): 5.17e-150: 494: 11.66
+	Hs
		730431 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		ABL2_HUMAN (84-1028): 1.08e-138: 459: 15.72
+	Hs
		730601 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		ERBB4_HUMAN (17-748): 2.34e-131: 442: 18.30
+	Hs
		840942 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		ABL2_HUMAN (84-1028): 1.08e-138: 459: 15.72
+	Hs
		362181 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		ABL1_HUMAN (84-931): 8.08e-117: 397: 18.90
+	Hs
		730582 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		FAK2_HUMAN (66-696): 1.74e-117: 396: 17.39
+	At
		1375563 14337_ARATH (2-247): 4.37e-147: 413: 58.07		SERK1_ARATH (1-436): 4.24e-130: 419: 18.94
+	Hs
		179597 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		MUSK_HUMAN (18-420): 2.44e-110: 373: 23.19
+	Hs
		362231 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		ABL1_HUMAN (84-931): 8.08e-117: 397: 18.90
+	Hs
		179602 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		MUSK_HUMAN (18-420): 2.44e-110: 373: 23.19
+	Hs
		411448 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		439660 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		INSR_HUMAN (93-407): 2.86e-34: 145: 32.82
+	Hs
		465425 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		IGF1R_HUMAN (131-399): 1.23e-33: 144: 33.33
+	Hs
		730542 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		ITK_HUMAN (137-407): 1.92e-32: 137: 34.19
+	Hs
		730613 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		NTRK3_HUMAN (131-410): 1.25e-31: 136: 28.25
+	Hs
		730458 1433S_HUMAN (1-248): 3.5e-158: 440: 100.00		BMX_HUMAN (131-411): 1.02e-31: 135: 31.56
+	Hs
		411694 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		NTRK1_HUMAN (131-410): 1.29e-36: 152: 33.33
+	Hs
		465471 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		IGF1R_HUMAN (131-399): 1.23e-33: 144: 33.33
+	Hs
		971443 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		ITK_HUMAN (137-407): 1.92e-32: 137: 34.19
+	Hs
		908193 1433E_HUMAN (2-246): 4.43e-146: 410: 60.41		BMX_HUMAN (131-411): 1.02e-31: 135: 31.56