HitPredict

Interactor 1: NUP62 (P37198)
Nuclear pore glycoprotein p62 (62 kDa nucleoporin) (Nucleoporin Nup62)
Gene: NUP62

Interactor 2: NTF2 (P61970)
Nuclear transport factor 2 (NTF-2) (Placental protein 15) (PP15)
Gene: NUTF2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.93	0.60	0.748

Property	Details
Experiments	25416956, 16730000, 32296183, 8707840, 7744965, 31515488, unassigned1304
Identification Methods	two hybrid, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006606 - protein import into nucleus GO:0017056 - structural constituent of nuclear pore GO:0031965 - nuclear membrane GO:0044613 - nuclear pore central transport channel and 1 others more... GO:0051028 - mRNA transport
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 127
+	Hs
		740144 NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		740279 NUP62_HUMAN (1-522): 3.62e-81: 264: 100.00		G3BP2_HUMAN (4-127): 5.6e-50: 166: 25.93
+	Mm
		903861 NUP62_MOUSE (1-522): 2.42e-67: 228: 74.19		NTF2_MOUSE (1-127): 3.29e-51: 160: 100.00
+	Mm
		1144385 NUP62_MOUSE (1-522): 2.42e-67: 228: 74.19		NXT1_MOUSE (6-123): 7.19e-39: 129: 23.44
+	Sc
		541862 NSP1_YEAST (30-504): 3.31e-29: 124: 16.02		NTF2_YEAST (3-122): 3.22e-42: 137: 42.62
+	Hs
		857971 NUP98_HUMAN (2-334): 2.75e-13: 75.1: 16.39		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96
+	Hs
		867095 SC24C_HUMAN (51-325): 4.69e-13: 74: 12.73		G3BP1_HUMAN (4-127): 3.72e-50: 166: 22.96