HitPredict

Interactor 1: AP2A (P38065)
AP-2 complex subunit alpha (Alpha-adaptin) (Clathrin assembly protein complex 2 alpha large chain) (Clathrin assembly protein large alpha chain)
Gene: APL3

Interactor 2: AP2M (Q99186)
AP-2 complex subunit mu (Adaptin medium chain APM4) (Clathrin assembly protein complex 2 mu medium chain) (Clathrin coat assembly protein AP50) (Clathrin coat-associated protein AP50) (Mu2-adaptin) (Plasma membrane adaptor AP-2 50 kDa protein)
Gene: APM4

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.83 1.00 0.916

The method score is based on:

Property Details
Experiments 11805826, 16554755, 37968396, 22940862, 16429126
Identification Methods tandem affinity purification, affinity chromatography technology
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Adap_comp_sub~Adaptin_N
Common GO terms GO:0006886 - intracellular protein transport
GO:0030122 - AP-2 adaptor complex
GO:0035615 - clathrin adaptor activity
GO:0072583 - clathrin-dependent endocytosis
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 1025
Sc

1 491
+ Rn
+ Hs
+ Hs
+ Dm
+ Ce
+ At
+ At
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024