HitPredict

Interactor 1: ATG8 (P38182)
Autophagy-related protein 8 (Autophagy-related ubiquitin-like modifier ATG8) (Cytoplasm to vacuole targeting protein 5)
Gene: ATG8

Interactor 2: ATG7 (P38862)
Ubiquitin-like modifier-activating enzyme ATG7 (ATG12-activating enzyme E1 ATG7) (Autophagy-related protein 7) (Cytoplasm to vacuole targeting protein 2)
Gene: ATG7

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.97 1.00 0.990

The method score is based on:

Property Details
Experiments 22056771, 11139573, 23142976, 11100732, 10688190, 12965207, 27477278, 29237558, 38057553, 22055191, 32453403, 18719252, 19398890, 22325599, 25042851
Identification Methods molecular sieving, x-ray crystallography, comigration in sds page, coimmunoprecipitation, anti tag coimmunoprecipitation, two hybrid, affinity chromatography technology, pull down
Interaction Type covalent binding, direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ATG8~ThiF
Common GO terms GO:0000045 - autophagosome assembly
GO:0000407 - phagophore assembly site
GO:0000422 - autophagy of mitochondrion
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 5 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 117
Sc

1 630
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+ Ce
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024