HitPredict

Interactor 1: GRP75 (P38646)
Stress-70 protein, mitochondrial (75 kDa glucose-regulated protein) (GRP-75) (Heat shock 70 kDa protein 9) (Heat shock protein family A member 9) (Mortalin) (MOT) (Peptide-binding protein 74) (PBP74)
Gene: HSPA9

Interactor 2: KS6B2 (Q9UBS0)
Ribosomal protein S6 kinase beta-2 (S6K-beta-2) (S6K2) (EC 2.7.11.1) (70 kDa ribosomal protein S6 kinase 2) (P70S6K2) (p70-S6K 2) (S6 kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14B) (p70 ribosomal S6 kinase beta) (S6K-beta) (p70 S6 kinase beta) (p70 S6K-beta) (p70 S6KB) (p70-beta)
Gene: RPS6KB2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25324306
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 679 Hs			1 482
+	Hs
		504896 HSP7C_HUMAN (51-653): 0: 883: 50.16		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Hs
		564201 HSP76_HUMAN (49-673): 0: 875: 48.68		KS6B2_HUMAN (1-482): 0: 531: 100.00
+	Dm
		669847 HSP7E_DROME (42-678): 0: 949: 77.05		AKT1_DROME (19-395): 5.26e-150: 442: 39.37
+	Hs
		503528 HSP7C_HUMAN (51-653): 0: 883: 50.16		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		503390 HSP7C_HUMAN (51-653): 0: 883: 50.16		KPCA_HUMAN (9-401): 2.4e-148: 440: 35.82
+	Hs
		564016 HSP76_HUMAN (49-673): 0: 875: 48.68		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Hs
		503922 HSP7C_HUMAN (51-653): 0: 883: 50.16		KPCE_HUMAN (2-395): 2.02e-145: 435: 34.23
+	Hs
		681702 GRP75_HUMAN (1-679): 0: 873: 100.00		AKT1_HUMAN (5-391): 6.01e-153: 445: 39.19
+	Mm
		554912 HS71A_MOUSE (51-652): 0: 867: 48.94		KPCE_MOUSE (2-395): 5.27e-145: 434: 33.74
+	Hs
		503719 HSP7C_HUMAN (51-653): 0: 883: 50.16		KS6A3_HUMAN (5-380): 2.45e-105: 331: 26.85
+	Hs
		504119 HSP7C_HUMAN (51-653): 0: 883: 50.16		KS6A1_HUMAN (5-380): 2.15e-105: 331: 25.19
+	Hs
		564041 HSP76_HUMAN (49-673): 0: 875: 48.68		KS6A3_HUMAN (5-380): 2.45e-105: 331: 26.85
+	Hs
		564080 HSP76_HUMAN (49-673): 0: 875: 48.68		KS6A1_HUMAN (5-380): 2.15e-105: 331: 25.19
+	Hs
		751545 GRP75_HUMAN (1-679): 0: 873: 100.00		KS6A3_HUMAN (5-380): 2.45e-105: 331: 26.85
+	Sc
		477838 HSP77_YEAST (37-653): 0: 785: 66.61		YPK1_YEAST (54-397): 2.05e-97: 309: 46.40
+	Sc
		477878 HSP77_YEAST (37-653): 0: 785: 66.61		YPK2_YEAST (67-403): 2.78e-96: 306: 47.93
+	Sc
		579938 HSP7E_YEAST (29-653): 0: 766: 63.43		YPK2_YEAST (67-403): 2.78e-96: 306: 47.93
+	Dm
		669818 BIP_DROME (53-641): 0: 566: 53.25		Q94533_DROME (43-480): 1.84e-161: 467: 63.24
+	Dm
		669813 BIP_DROME (53-641): 0: 566: 53.25		AKT1_DROME (19-395): 5.26e-150: 442: 39.37
+	Mm
		554943 Q9DC41_MOUSE (53-677): 0: 566: 51.81		KPCE_MOUSE (2-395): 5.27e-145: 434: 33.74