HitPredict

Interactor 1: DCA13 (P33750)
Protein SOF1 (U3 small nucleolar RNA-associated protein SOF1) (U3 snoRNA-associated protein SOF1)
Gene: SOF1

Interactor 2: DOA1 (P36037)
Protein DOA1 (Degradation of alpha protein 1) (Ubiquitin fusion degradation protein 3)
Gene: DOA1

Species: Saccharomyces cerevisiae S288C

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26349035
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Sof1~WD40, WD40~WD40
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 489 Sc			1 715
+	Sc
		754333 DCA13_YEAST (1-489): 1.49e-120: 363: 100.00		UTP13_YEAST (10-246): 5.09e-18: 90.9: 30.30
+	Hs
		1380064 FBXW7_HUMAN (148-441): 8.28e-64: 221: 12.77		FBXW7_HUMAN (205-565): 2.63e-45: 174: 13.93
+	Hs
		965141 FBXW7_HUMAN (148-441): 8.28e-64: 221: 12.77		WDR5_HUMAN (288-531): 5.36e-31: 126: 10.36
+	Sc
		673545 NLE1_YEAST (164-482): 1.06e-57: 200: 11.84		NLE1_YEAST (4-165): 1.14e-32: 134: 15.94
+	Dm
		1463899 WDS_DROME (3-293): 4.78e-59: 200: 14.19		WDS_DROME (290-531): 1.68e-30: 125: 9.64
+	Hs
		845264 LIS1_HUMAN (1-250): 1.12e-46: 168: 14.67		WDR5_HUMAN (288-531): 5.36e-31: 126: 10.36
+	Mm
		988931 LIS1_MOUSE (1-250): 8.55e-47: 169: 14.67		LIS1_MOUSE (311-534): 1.26e-25: 111: 8.84
+	Hs
		845250 LIS1_HUMAN (1-250): 1.12e-46: 168: 14.67		LIS1_HUMAN (311-534): 1.47e-25: 111: 8.84
+	Hs
		964797 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		WDR5_HUMAN (288-531): 5.36e-31: 126: 10.36
+	Dm
		1463923 WDS_DROME (3-293): 4.78e-59: 200: 14.19		FBXW7_DROME (288-454): 3.7e-13: 75.4: 13.45
+	Hs
		965071 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		WDR5B_HUMAN (365-619): 2.31e-21: 97.7: 11.90
+	Hs
		965276 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		NLE1_HUMAN (4-82): 2.33e-19: 93.9: 22.50
+	Hs
		1450936 NLE1_HUMAN (288-486): 4.13e-35: 138: 14.15		NLE1_HUMAN (4-82): 2.33e-19: 93.9: 22.50
+	Hs
		965151 WDR5_HUMAN (5-247): 2.17e-41: 152: 12.31		SNR40_HUMAN (398-629): 3.55e-09: 61.1: 7.63
+	Hs
		1334151 POC1B_HUMAN (5-192): 5.12e-25: 109: 15.90		POC1A_HUMAN (3-82): 6.8e-17: 85.4: 17.28
+	Hs
		1387527 WDR83_HUMAN (59-381): 2.12e-26: 111: 18.49		SNR40_HUMAN (398-629): 3.55e-09: 61.1: 7.63